Solokhina, Anna and Bonkat, Gernot and Braissant, Olivier. (2019) Measuring the Metabolic Activity of Mature Mycobacterial Biofilms Using Isothermal Microcalorimetry. Methods in molecular biology (Clifton, N.J.), 1964. pp. 141-149.
Full text not available from this repository.
Official URL: https://edoc.unibas.ch/78923/
Downloads: Statistics Overview
Abstract
Measuring metabolic activity and response of biofilm to different conditions or compounds is of general interest but is also expected to help in developing new antibiofilm compounds and potentially new treatments. Current culture-based and microscopic methods although of much use have several drawbacks. Isothermal calorimetry can be useful in this context by allowing measurements of the metabolic activity of biofilm grown and maintained on solid medium. Biofilms prepared on membranes were placed in calorimetry vials containing solid medium. Sealed vials were introduced in an isothermal calorimeter, and the rate of metabolic heat production was monitored over time. We chose mycobacteria as an example for this paper as working with mycobacterial biofilms is notoriously difficult.
Faculties and Departments: | 03 Faculty of Medicine > Departement Biomedical Engineering |
---|---|
UniBasel Contributors: | Braissant, Olivier |
Item Type: | Article, refereed |
Article Subtype: | Research Article |
ISSN: | 1940-6029 |
Note: | Publication type according to Uni Basel Research Database: Journal article |
Identification Number: |
|
Last Modified: | 03 Nov 2020 15:30 |
Deposited On: | 03 Nov 2020 15:30 |
Repository Staff Only: item control page