Sexually transmitted coinfections in patients with anogenital warts - a retrospective analysis of 196 patients

Mueller, Simon M. and Menzi, Sheryl and Kind, André B. and Blaich, Annette and Bayer, Michael and Navarini, Alexander and Itin, Peter and Brandt, Oliver. (2020) Sexually transmitted coinfections in patients with anogenital warts - a retrospective analysis of 196 patients. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 18 (4). pp. 325-332.

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Official URL: https://edoc.unibas.ch/76711/

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Anogenital warts (AGWs) are most commonly caused by low-risk human papillomavirus (HPV) types, and although they are the most frequent viral sexually transmitted infections (STIs), little is known about STI coinfections in affected patients. We therefore sought to assess STI coinfection rates in patients with AGW, specify STI coinfections and calculate the number needed to screen (NNS) for each STI.; A retrospective cross-sectional study analyzing data sets from AGW patients treated in our clinic between 2008-2016.; 142/196 (72 %) patients had been variably screened for infections with HIV, HBV and HCV, Treponema pallidum, Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma genitalium and HSV. The STI coinfection rate in all tested patients was 24.6 %, yielding an NNS of 4.1 to detect any STI. Of note, the coinfection rate did not differ significantly between heterosexual men, homosexual men and women, respectively. The NNS for syphilis was 8.4, for HIV 14.0, for HCV 28.5 and for HBV 39.0. The NNS for asymptomatic patients tested for HSV, Chlamydia trachomatis and Mycoplasma genitalium were 1.4, 5.3 and 12.0, respectively.; Due to the high prevalence of STI coinfections, AGW patients should be screened for other STIs.
Faculties and Departments:03 Faculty of Medicine > Bereich Spezialfächer (Klinik) > Dermatologie USB > Dermatologie (Navarini)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Spezialfächer (Klinik) > Dermatologie USB > Dermatologie (Navarini)
UniBasel Contributors:Navarini, Alexander
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:29 Dec 2020 15:21
Deposited On:29 Dec 2020 15:21

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