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Adverse cardiovascular effects of traffic noise with a focus on nighttime noise and the new WHO noise guidelines

Münzel, Thomas and Kröller-Schön, Swenja and Oelze, Matthias and Gori, Tommaso and Schmidt, Frank P. and Steven, Sebastian and Hahad, Omar and Röösli, Martin and Wunderli, Jean-Marc and Daiber, Andreas and Sørensen, Mette. (2020) Adverse cardiovascular effects of traffic noise with a focus on nighttime noise and the new WHO noise guidelines. Annual review of public health, 41. pp. 309-328.

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Official URL: https://edoc.unibas.ch/76452/

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Abstract

Exposure to traffic noise is associated with stress and sleep disturbances. The World Health Organization (WHO) recently concluded that road traffic noise increases the risk for ischemic heart disease and potentially other cardiometabolic diseases, including stroke, obesity, and diabetes. The WHO report focused on whole-day noise exposure, but new epidemiological and translational field noise studies indicate that nighttime noise, in particular,is an important risk factor for cardiovascular disease (CVD) through increased levels of stress hormones and vascular oxidative stress, leading to endothelial dysfunction and subsequent development of various CVDs. Novel experimental studies found noise to be associated with oxidative stress-induced vascular and brain damage, mediated by activation of the NADPH oxidase, uncoupling of endothelial and neuronal nitric oxide synthase, and vascular/brain infiltration with inflammatory cells. Noise-induced pathophysiology was more pronounced in response to nighttime as compared with daytime noise. This review focuses on the consequences of nighttime noise.
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Environmental Exposures and Health > Physical Hazards and Health (Röösli)
UniBasel Contributors:Röösli, Martin
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Annual Reviews Inc.
ISSN:0163-7525
Note:Publication type according to Uni Basel Research Database: Journal article
Identification Number:
Last Modified:24 Apr 2020 06:46
Deposited On:24 Apr 2020 06:46

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