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Reconstitution of Channel Proteins in (Polymerized) ABA Triblock Copolymer Membranes

Meier, Wolfgang and Nardin, Corinne and Winterhalter, Mathias. (2000) Reconstitution of Channel Proteins in (Polymerized) ABA Triblock Copolymer Membranes. Angewandte Chemie International Edition, 39 (24). pp. 4599-4602.

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Official URL: https://edoc.unibas.ch/72388/

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Abstract

A new class of mechanically stable block copolymer protein hybrid materials: Giant freestanding membranes with a thickness of 10 nm were prepared from polymerizable amphiphilic triblock copolymers in which, despite their extreme thickness, it was possible to reconstitute channel proteins. The proteins remained functional in the completely artificial surrounding even after polymerization of the membranes, as revealed by conductance measurements. These polymerâEuro"protein hybrid materials possess great potential for applications in the area of diagnostics, sensor technology, protein crystallization, and even drug delivery.
Faculties and Departments:05 Faculty of Science > Departement Chemie
05 Faculty of Science > Departement Chemie > Chemie > Makromolekulare Chemie (Meier)
UniBasel Contributors:Meier, Wolfgang P.
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Wiley
ISSN:1433-7851
e-ISSN:1521-3773
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:23 Mar 2020 17:08
Deposited On:23 Mar 2020 17:08

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