Thermography: High sensitivity and specificity diagnosing contact dermatitis in patch testing

Anzengruber, Florian and Alotaibi, Fayez and Kaufmann, Lilian S. and Ghosh, Adhideb and Oswald, Martin R. and Maul, Julia-Tatjana and Meier, Barbara and French, Lars E. and Bonmarin, Mathias and Navarini, Alexander A.. (2019) Thermography: High sensitivity and specificity diagnosing contact dermatitis in patch testing. Allergology international, 68 (2). pp. 254-258.

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Official URL: https://edoc.unibas.ch/72189/

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Patch testing of contact allergens to diagnose allergic contact dermatitis (ACD) is a traditional, useful tool. The most important decision is the distinction between allergic and irritant reactions, as this has direct implications on diagnosis and management. Our objective was to evaluate a new method of non-contact infrared reading of patch tests. Secondary objectives included a possible correlation between the intensity of the patch test reaction and temperature change.; 420 positive reactions from patients were included in our study. An independent patch test reader assessed the positive reactions and classified them as allergic (of intensity + to +++) or irritant (IR). At the same time, a forward-looking infrared (FLIR) camera attachment for an iPhone was used to acquire infrared thermal images of the patch tests, and images were analyzed using the FLIR ONE app.; Allergic patch test reactions were characterized by temperature increases of 0.72 ± 0.67 °C compared to surrounding skin. Irritant reactions only resulted in 0.17 ± 0.31 °C temperature increase. The mean temperature difference between the two groups was highly significant (p < 0.0001) and therefore was used to predict the type of contact dermatitis.; Thermography is a reliable and effective way to distinguish between allergic and irritant contact dermatitis.
Faculties and Departments:03 Faculty of Medicine > Bereich Spezialfächer (Klinik) > Dermatologie USB > Dermatologie (Navarini)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Spezialfächer (Klinik) > Dermatologie USB > Dermatologie (Navarini)
UniBasel Contributors:Navarini, Alexander
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:The Japanese Society of Allergology
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:10 Jul 2020 09:05
Deposited On:10 Jul 2020 09:05

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