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Novel monomers in radical ring-opening polymerisation for biodegradable and pH responsive nanoparticles

Folini, Jenny and Huang, Chao-Hung and Anderson, James C. and Meier, Wolfgang P. and Gaitzsch, Jens. (2019) Novel monomers in radical ring-opening polymerisation for biodegradable and pH responsive nanoparticles. Polymer Chemistry, 10 (39). pp. 5285-5288.

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Official URL: https://edoc.unibas.ch/72151/

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Abstract

Responsive and biodegradable nanoparticles are essential for functional drug delivery systems. We herein report the first pH sensitive polyester from radical ring-opening polymerisation of novel amine-bearing cyclic ketene acetals (CKAs). The CKAs were synthesised via an intermediate carbonate and the resulting polyesters showed a pKa around pH 6. Together with an initial application in biodegradable nanoparticles,
Faculties and Departments:05 Faculty of Science > Departement Chemie
05 Faculty of Science > Departement Chemie > Chemie > Makromolekulare Chemie (Meier)
UniBasel Contributors:Meier, Wolfgang P. and Gaitzsch, Jens
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Royal Society of Chemistry
ISSN:1759-9954
e-ISSN:1759-9962
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
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Last Modified:22 Oct 2019 09:17
Deposited On:15 Oct 2019 08:24

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