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Terpenoids and phenolics of Micromeria persica

Kalaki Kordkolaei, Sakineh and Kanani, Mohammad Reza and Tabefam, Marzieh and Sarvestani, Nazanin Namazi and Hamburger, Matthias and Moridi Farimani, Mahdi. (2020) Terpenoids and phenolics of Micromeria persica. Natural Product Research, 34 (20). pp. 2913-2918.

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Official URL: https://edoc.unibas.ch/70827/

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Abstract

Phytochemical investigation of the aerial parts of Micromeria persica led to the isolation of a new oleane type triterpenoid ester (1), together with six known compounds 2–7), comprising one phenyl ethanoid ester, one glycosylated flavonoid, two triterpenoids, and two steroids. Their structures were elucidated by interpretation of their one-dimensional and two-dimensional NMR spectra and completed by the analysis of the HRESIMS data. Compounds 1 and 3 were evaluated for their cytotoxic feature against human breast adenocarcinoma cell line (MDA-MB231) and human prostate cancer cell line (DU145). However, they did not show positive effect (IC50 > 75µM).
Faculties and Departments:05 Faculty of Science > Departement Pharmazeutische Wissenschaften > Ehemalige Einheiten Pharmazie > Pharmazeutische Biologie (Hamburger)
UniBasel Contributors:Hamburger, Matthias
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Taylor & Francis
ISSN:1478-6419
e-ISSN:1478-6427
Note:Publication type according to Uni Basel Research Database: Journal article
Identification Number:
Last Modified:01 Nov 2021 16:11
Deposited On:17 Aug 2020 12:48

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