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The role of socioeconomic status in the association of lung function and air pollution-a pooled analysis of three adult ESCAPE cohorts

Keidel, Dirk and Anto, Josep Maria and Basagaña, Xavier and Bono, Roberto and Burte, Emilie and Carsin, Anne-Elie and Forsberg, Bertil and Fuertes, Elaine and Galobardes, Bruna and Heinrich, Joachim and de Hoogh, Kees and Jarvis, Debbie and Künzli, Nino and Leynaert, Bénédicte and Marcon, Alessandro and Le Moual, Nicole and de Nazelle, Audrey and Schindler, Christian and Siroux, Valérie and Stempfelet, Morgane and Sunyer, Jordi and Temam, Sofia and Tsai, Ming-Yi and Varraso, Raphaëlle and Jacquemin, Bénédicte and Probst-Hensch, Nicole. (2019) The role of socioeconomic status in the association of lung function and air pollution-a pooled analysis of three adult ESCAPE cohorts. International journal of environmental research and public health, 16 (11). p. 1901.

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Abstract

Ambient air pollution is a leading environmental risk factor and its broad spectrum of adverse health effects includes a decrease in lung function. Socioeconomic status (SES) is known to be associated with both air pollution exposure and respiratory function. This study assesses the role of SES either as confounder or effect modifier of the association between ambient air pollution and lung function. Cross-sectional data from three European multicenter adult cohorts were pooled to assess factors associated with lung function, including annual means of home outdoor NO; 2; . Pre-bronchodilator lung function was measured according to the ATS-criteria. Multiple mixed linear models with random intercepts for study areas were used. Three different factors (education, occupation and neighborhood unemployment rate) were considered to represent SES. NO; 2; exposure was negatively associated with lung function. Occupation and neighborhood unemployment rates were not associated with lung function. However, the inclusion of the SES-variable education improved the models and the air pollution-lung function associations got slightly stronger. NO; 2; associations with lung function were not substantially modified by SES-variables. In this multicenter European study we could show that SES plays a role as a confounder in the association of ambient NO; 2; exposure with lung function.
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Chronic Disease Epidemiology > Air Pollution and Health (Künzli)
03 Faculty of Medicine > Departement Public Health > Sozial- und Präventivmedizin > Air Pollution and Health (Künzli)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Chronic Disease Epidemiology > Genetic Epidemiology of Non-Communicable Diseases (Probst-Hensch)
03 Faculty of Medicine > Departement Public Health > Sozial- und Präventivmedizin > Genetic Epidemiology of Non-Communicable Diseases (Probst-Hensch)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH)
UniBasel Contributors:Keidel, Dirk and de Hoogh, Kees and Künzli, Nino and Probst Hensch, Nicole
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:MDPI
ISSN:1661-7827
e-ISSN:1660-4601
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
Identification Number:
Last Modified:28 Jun 2019 15:17
Deposited On:28 Jun 2019 15:17

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