Incidence rates and trends of hip/femur fractures in five European countries: comparison using e-healthcare records databases

Requena, G. and Abbing-Karahagopian, V. and Huerta, C. and De Bruin, M. L. and Alvarez, Y. and Miret, M. and Hesse, U. and Gardarsdottir, H. and Souverein, P. C. and Slattery, J. and Schneider, C. and Rottenkolber, M. and Schmiedl, S. and Gil, M. and De Groot, M. C. H. and Bate, A. and Ruigómez, A. and García Rodríguez, L. A. and Johansson, S. and de Vries, F. and Montero, D. and Schlienger, R. and Reynolds, R. and Klungel, O. H. and de Abajo, F. J.. (2014) Incidence rates and trends of hip/femur fractures in five European countries: comparison using e-healthcare records databases. Calcified tissue international, 94 (6). pp. 580-589.

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Official URL: https://edoc.unibas.ch/70461/

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Hip fractures represent a major public health challenge worldwide. Multinational studies using a common methodology are scarce. We aimed to estimate the incidence rates (IRs) and trends of hip/femur fractures over the period 2003-2009 in five European countries. The study was performed using seven electronic health-care records databases (DBs) from Denmark, The Netherlands, Germany, Spain, and the United Kingdom, based on the same protocol. Yearly IRs of hip/femur fractures were calculated for the general population and for those aged ≥50 years. Trends over time were evaluated using linear regression analysis for both crude and standardized IRs. Sex- and age-standardized IRs for the UK, Netherlands, and Spanish DBs varied from 9 to 11 per 10,000 person-years for the general population and from 22 to 26 for those ≥50 years old; the German DB showed slightly higher IRs (about 13 and 30, respectively), whereas the Danish DB yielded IRs twofold higher (19 and 52, respectively). IRs increased exponentially with age in both sexes. The ratio of females to males was ≥2 for patients aged ≥70-79 years in most DBs. Statistically significant trends over time were only shown for the UK DB (CPRD) (+0.7% per year, P < 0.01) and the Danish DB (-1.4% per year, P < 0.01). IRs of hip/femur fractures varied greatly across European countries. With the exception of Denmark, no decreasing trend was observed over the study period.
Faculties and Departments:03 Faculty of Medicine > Bereich Querschnittsfächer (Klinik) > Spital-Pharmazie > Spitalpharmazie (Meier)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Querschnittsfächer (Klinik) > Spital-Pharmazie > Spitalpharmazie (Meier)
UniBasel Contributors:Schneider, Cornelia
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:31 May 2020 21:02
Deposited On:31 May 2020 21:02

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