Feng, Jianhao and Hevey, Rachel and Ling, Chang-Chun. (2011) Synthesis of a Forssman antigen derivative for use in a conjugate vaccine. Carbohydrate Research, 346 (17). pp. 2650-2662.
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Official URL: https://edoc.unibas.ch/70098/
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Abstract
The total chemical synthesis of a Forssman antigen analog is described. The pentasaccharide contains a functionalized tether which should facilitate future conjugation with immunogenic proteins. We found that the total synthesis can be efficiently achieved by following a convergent 2+3 strategy, and using N-Troc protected GalNAc thioglycoside as a donor.
| Faculties and Departments: | 05 Faculty of Science > Departement Pharmazeutische Wissenschaften > Ehemalige Einheiten Pharmazie > Molekulare Pharmazie (Ernst) 05 Faculty of Science > Departement Pharmazeutische Wissenschaften > Pharmazie > Molecular Pharmacy (Ricklin) |
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| UniBasel Contributors: | Hevey, Rachel |
| Item Type: | Article, refereed |
| Article Subtype: | Research Article |
| Publisher: | Elsevier |
| ISSN: | 0008-6215 |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
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| Identification Number: |
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| Last Modified: | 16 Nov 2020 10:21 |
| Deposited On: | 16 Nov 2020 10:21 |
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