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Case report : two cases of cholangiocarcinoma in patients with Opisthorchis felineus infection in Western Siberia, Russian Federation

Kovshirina, Yulia V. and Fedorova, Olga S. and Vtorushin, Sergey V. and Kovshirina, Anna E. and Ivanov, Stanislav D. and Chizhikov, Andrey V. and Onishchenko, Sergey V. and Ogorodova, Ludmila M. and Odermatt, Peter. (2019) Case report : two cases of cholangiocarcinoma in patients with Opisthorchis felineus infection in Western Siberia, Russian Federation. American journal of tropical medicine and hygiene, 100 (3). pp. 599-603.

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Official URL: https://edoc.unibas.ch/69851/

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Abstract

Cholangiocarcinoma (CCA) is a cancer with high mortality owing to its aggressiveness and resistance to therapy. The liver flukes of the Opisthorchiidae family have been recognized as risk factors of CCA.; Opisthorchis felineus; infection occurs in Western Siberia, the biggest endemic area in the Russian Federation, and is associated with chronic inflammation of the bile ducts, which may be linked to severe hepatobiliary morbidity. We report two cases of confirmed CCA who had a chronic; O. felineus; infection. Both cases presented unspecific symptoms at the onset of the disease, a stage when severe pathological changes already had occurred. Both patients were living in endemic areas but did not receive any antihelminthic treatment. This report underlines the need for assessment of; O. felineus; infection as a causative factor of CCA. The results will provide further arguments for control of; O. felineus; in the Russian Federation.
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Eco System Health Sciences > Health Impact Assessment (Utzinger)
UniBasel Contributors:Odermatt, Peter
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Williams and Wilkins
ISSN:0002-9637
Note:Publication type according to Uni Basel Research Database: Journal article
Identification Number:
Last Modified:20 Mar 2019 13:54
Deposited On:20 Mar 2019 13:54

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