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Second-hand smoke exposure in adulthood and lower respiratory health during 20 year follow up in the European Community Respiratory Health Survey

Flexeder, Claudia and Zock, Jan-Paul and Jarvis, Deborah and Verlato, Giuseppe and Olivieri, Mario and Benke, Geza and Abramson, Michael J. and Sigsgaard, Torben and Svanes, Cecilie and Torén, Kjell and Nowak, Dennis and Jõgi, Rain and Martinez-Moratalla, Jesús and Demoly, Pascal and Janson, Christer and Gislason, Thorarinn and Bono, Roberto and Holm, Mathias and Franklin, Karl A. and Garcia-Aymerich, Judith and Siroux, Valérie and Leynaert, Bénédicte and Dorado Arenas, Sandra and Corsico, Angelo Guido and Pereira-Vega, Antonio and Probst-Hensch, Nicole and Urrutia Landa, Isabel and Schulz, Holger and Heinrich, Joachim. (2019) Second-hand smoke exposure in adulthood and lower respiratory health during 20 year follow up in the European Community Respiratory Health Survey. Respiratory research, 20. p. 33.

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Official URL: https://edoc.unibas.ch/69657/

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Abstract

Early life exposure to tobacco smoke has been extensively studied but the role of second-hand smoke (SHS) for new-onset respiratory symptoms and lung function decline in adulthood has not been widely investigated in longitudinal studies. Our aim is to investigate the associations of exposure to SHS in adults with respiratory symptoms, respiratory conditions and lung function over 20 years.; We used information from 3011 adults from 26 centres in 12 countries who participated in the European Community Respiratory Health Surveys I-III and were never or former smokers at all three surveys. Associations of SHS exposure with respiratory health (asthma symptom score, asthma, chronic bronchitis, COPD) were analysed using generalised linear mixed-effects models adjusted for confounding factors (including sex, age, smoking status, socioeconomic status and allergic sensitisation). Linear mixed-effects models with additional adjustment for height were used to assess the relationships between SHS exposure and lung function levels and decline.; Reported exposure to SHS decreased in all 26 study centres over time. The prevalence of SHS exposure was 38.7% at baseline (1990-1994) and 7.1% after the 20-year follow-up (2008-2011). On average 2.4% of the study participants were not exposed at the first, but were exposed at the third examination. An increase in SHS exposure over time was associated with doctor-diagnosed asthma (odds ratio (OR): 2.7; 95% confidence interval (95%-CI): 1.2-5.9), chronic bronchitis (OR: 4.8; 95%-CI: 1.6-15.0), asthma symptom score (count ratio (CR): 1.9; 95%-CI: 1.2-2.9) and dyspnoea (OR: 2.7; 95%-CI: 1.1-6.7) compared to never exposed to SHS. Associations between increase in SHS exposure and incidence of COPD (OR: 2.0; 95%-CI: 0.6-6.0) or lung function (β: - 49 ml; 95%-CI: -132, 35 for FEV; 1; and β: - 62 ml; 95%-CI: -165, 40 for FVC) were not apparent.; Exposure to second-hand smoke may lead to respiratory symptoms, but this is not accompanied by lung function changes.
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Chronic Disease Epidemiology > Genetic Epidemiology of Non-Communicable Diseases (Probst-Hensch)
03 Faculty of Medicine > Departement Public Health > Sozial- und Präventivmedizin > Genetic Epidemiology of Non-Communicable Diseases (Probst-Hensch)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH)
UniBasel Contributors:Probst Hensch, Nicole
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:BioMed Central
ISSN:1465-9921
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
Identification Number:
Last Modified:06 Mar 2019 08:11
Deposited On:06 Mar 2019 08:11

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