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Cancer Diagnosis Using a Liquid Biopsy: Challenges and Expectations

Castro-Giner, Francesc and Gkountela, Sofia and Donato, Cinzia and Alborelli, Ilaria and Quagliata, Luca and Ng, Charlotte K. Y. and Piscuoglio, Salvatore and Aceto, Nicola. (2018) Cancer Diagnosis Using a Liquid Biopsy: Challenges and Expectations. Diagnostics, 8 (2). p. 31.

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Abstract

The field of cancer diagnostics has recently been impacted by new and exciting developments in the area of liquid biopsy. A liquid biopsy is a minimally invasive alternative to surgical biopsies of solid tissues, typically achieved through the withdrawal of a blood sample or other body fluids, allowing the interrogation of tumor-derived material including circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA) fragments that are present at a given time point. In this short review, we discuss a few studies that summarize the state-of-the-art in the liquid biopsy field from a diagnostic perspective, and speculate on current challenges and expectations of implementing liquid biopsy testing for cancer diagnosis and monitoring in the clinical setting.
Faculties and Departments:03 Faculty of Medicine
03 Faculty of Medicine > Bereich Querschnittsfächer (Klinik) > Pathologie USB
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Querschnittsfächer (Klinik) > Pathologie USB
UniBasel Contributors:Piscuoglio, Salvatore
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:MDPI
ISSN:2075-4418
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
Identification Number:
Last Modified:28 Jan 2019 13:30
Deposited On:28 Jan 2019 13:29

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