Stick-Slip Motion of ssDNA over Graphene

Vilhena, J. G. and Gnecco, Enrico and Pawlak, Remy and Moreno-Herrero, Fernando and Meyer, Ernst and Perez, Ruben. (2018) Stick-Slip Motion of ssDNA over Graphene. JOURNAL OF PHYSICAL CHEMISTRY B, 122 (2, SI). pp. 840-846.

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Official URL: https://edoc.unibas.ch/68103/

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We have performed molecular dynamics simulations of nanomanipulation experiments on short single-stranded DNA chains elastically driven on a graphene surface. After a brief transient, reproducible stick–slip cycles are observed on chains made by 10 units of thymine, cytosine, adenine, and guanine. The cycles have the periodicity of the graphene substrate, and take place via an intermediate stage, appearing as a dip in the sawtooth variations of lateral force recorded while the chains are manipulated. Guanine presents remarkable differences from the other bases, since a lower number of nucleotides are prone to stick to the substrate in this case. Nevertheless, the magnitudes of static friction and lateral stiffness are similar for all chains (30 pN and 0.7 N/m per adsorbed nucleotide respectively).
Faculties and Departments:05 Faculty of Science > Departement Physik > Physik > Nanomechanik (Meyer)
UniBasel Contributors:Meyer, Ernst
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:16 Oct 2019 15:01
Deposited On:08 Oct 2019 07:26

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