Müller, Thomas and Lang, Undine E. and Muhlack, Siegfried and Welnic, Jacub and Hellweg, Rainer. (2015) Impact of levodopa on reduced nerve growth factor levels in patients with Parkinson disease. Clinical neuropharmacology, 28 (5). pp. 238-240.
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Abstract
The author s found 6.5-fold reduced nerve growth factor (NGF) levels in the plasma of treated patients with Parkinson disease (PD) compared with healthy control subjects (P = 0.03). A significant positive correlation between levodopa and NGF plasma levels appeared after acute levodopa/benserazide administration. The data suggest that acute levodopa administration may contribute to an increase of NGF plasma concentrations, which are reduced in treated PD patients due to the ongoing disease process itself or chronic antiparkinsonian drug treatment.
| Faculties and Departments: | 03 Faculty of Medicine > Bereich Psychiatrie (Klinik) > Erwachsenenpsychiatrie UPK > Erwachsenenpsychiatrie (Lang) 03 Faculty of Medicine > Departement Klinische Forschung > Bereich Psychiatrie (Klinik) > Erwachsenenpsychiatrie UPK > Erwachsenenpsychiatrie (Lang) |
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| UniBasel Contributors: | Lang, Undine |
| Item Type: | Article, refereed |
| Article Subtype: | Research Article |
| Publisher: | Lippincott Williams & Wilkins |
| ISSN: | 0362-5664 |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
| Identification Number: |
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| Last Modified: | 30 Nov 2020 15:57 |
| Deposited On: | 30 Nov 2020 15:57 |
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