The endoplasmic reticulum-the caring mother of the cell

Spang, Anne. (2018) The endoplasmic reticulum-the caring mother of the cell. Current Opinion in Cell Biology, 53. pp. 92-96.

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In eukaryotic cells, various cellular functions are compartmentalized and performed by sophisticated and specialized organelles. However, the membrane-bounded organelles need to communicate with each other and with the cytoplasm, and sense the outside through the plasma membrane to coordinate various functions and to maintain cellular homeostasis. To maintain homeostasis, the information on the cellular state must be collected and appropriate responses initiated. The endoplasmic reticulum fulfils these functions. In this review, I will discuss various aspects of how the ER senses and relays information and acts to protect the cell, in what sometimes could be interpreted as an altruistic behavior.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Growth & Development > Biochemistry (Spang)
UniBasel Contributors:Spang, Anne
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:30 Dec 2020 09:03
Deposited On:10 Sep 2020 09:49

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