Müller, Cristina and Forrer, Flavio and Schibli, Roger and Krenning, Eric P. and de Jong, Marion. (2008) SPECT study of folate receptor-positive malignant and normal tissues in mice using a novel 99mTc-radiofolate. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 49 (2). pp. 310-317.
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Official URL: https://edoc.unibas.ch/63224/
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Abstract
The folate receptor (FR) is overexpressed on epithelial cancers (FR-alpha) and on activated, but not resting, macrophages (FR-beta) involved in a variety of inflammatory and autoimmune diseases. Therefore, folate-based radiopharmaceuticals have the potential to be used as imaging agents of FR-positive tumor and inflammatory cells. In this study SPECT/CT of FR-positive malignant and normal tissues and organs in mice was performed using an improved organometallic (99m)Tc-radiofolate.
| Faculties and Departments: | 03 Faculty of Medicine > Bereich Querschnittsfächer (Klinik) > Radiologie USB > Nuklearmedizin (Wild) 03 Faculty of Medicine > Departement Klinische Forschung > Bereich Querschnittsfächer (Klinik) > Radiologie USB > Nuklearmedizin (Wild) |
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| UniBasel Contributors: | Forrer, Flavio |
| Item Type: | Article, refereed |
| Article Subtype: | Research Article |
| Publisher: | Society of Nuclear Medicine |
| ISSN: | 0161-5505 |
| e-ISSN: | 1535-5667 |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
| Identification Number: |
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| Last Modified: | 10 Aug 2020 16:09 |
| Deposited On: | 10 Aug 2020 16:09 |
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