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Clinical value of SPECT/CT for evaluation of patients with painful knees after total knee arthroplasty - a new dimension of diagnostics?

Hirschmann, Michael T. and Konala, Praveen and Iranpour, Farhad and Kerner, Anna and Rasch, Helmut and Friederich, Niklaus F.. (2011) Clinical value of SPECT/CT for evaluation of patients with painful knees after total knee arthroplasty - a new dimension of diagnostics? BMC Musculoskeletal Disorders, 12. p. 36.

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Abstract

BACKGROUND: The purpose of our study was to evaluate the clinical value of hybrid SPECT/CT for the assessment of patients with painful total knee arthroplasty (TKA). METHODS: Twenty-three painful knees in patients following primary TKA were assessed using Tc-99m-HDP-SPECT/CT. Rotational, sagittal and coronal position of the TKA was assessed on 3D-CT reconstructions. The level of the SPECT-tracer uptake (0-10) and its anatomical distribution was mapped using a validated localization scheme. Univariate analysis (Wilcoxon-Mann-Whitney, Spearmean`s-rho test, p<0.05) was performed to identify any correlations between component position, tracer uptake and diagnosis. RESULTS: SPECT/CT imaging changed the suspected diagnosis and the proposed treatment in 19/23 (83%) knees. Progression of patellofemoral OA (n=11), loosening of the tibial (n=3) and loosening of the femoral component (n=2) were identified as the leading causes of pain after TKA. Patients with externally rotated tibial trays showed higher tracer uptake in the medial patellar facet (p=0.049) and in the femur (p=0.051). Patients with knee pain due to patellofemoral OA showed significantly higher tracer uptake in the patella than others (p<0.001). CONCLUSIONS: SPECT/CT was very helpful in establishing the diagnosis and guiding subsequent management in patients with painful knees after TKA, particularly in patients with patellofemoral problems and malpositioned or loose TKA.
Faculties and Departments:03 Faculty of Medicine > Bereich Operative Fächer (Klinik) > Bewegungsapparat und Integument
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Operative Fächer (Klinik) > Bewegungsapparat und Integument
UniBasel Contributors:Friederich, Niklaus F.
Item Type:Article, refereed
Article Subtype:Further Journal Contribution
Publisher:BioMed Central
e-ISSN:1471-2474
Note:Publication type according to Uni Basel Research Database: Journal item
Language:English
Identification Number:
Last Modified:06 Jun 2018 15:20
Deposited On:06 Jun 2018 15:20

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