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Multiple Sclerosis: Associations Between Physical Disability and Depression Are Not Mediated by Self-Reported Physical Activity

Merkt, Helene and Sadeghi Bahmani, Dena and Calabrese, Pasquale and Naegelin, Yvonne and Gerber, Markus and Pühse, Uwe and Holsboer-Trachsler, Edith and Brand, Serge. (2017) Multiple Sclerosis: Associations Between Physical Disability and Depression Are Not Mediated by Self-Reported Physical Activity. Perceptual and Motor Skills, 124 (5). pp. 974-991.

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Abstract

This study investigated the interrelatedness of physical disability, physical activity and depression among patients with Multiple Sclerosis (MS). We hypothesized that self-reported physical activity would mediate the effect of disability on depressive symptoms. Twenty-seven patients with MS (mean age: 49 years; 44.5% females) completed self-rating scales covering socio-demographic variables, intake of antidepressants, physical activity, and symptoms of depression; disability was measured by the Expanded Disability Status Scale (EDSS). We found a higher level of disability to be significantly associated with more symptoms of depression. While higher reported physical activity was descriptively associated with lower depression scores and unrelated to EDSS, physical activity levels did not mediate the effect of disability on depressive symptoms. We concluded that increased disability was associated with more symptoms of depression and that self-reported physical activity did not mediate this association even though higher physical activity was separately related to fewer depression symptoms.
Faculties and Departments:03 Faculty of Medicine > Departement Sport, Bewegung und Gesundheit > Bereich Sportwissenschaft > Sportwissenschaften (Pühse)
03 Faculty of Medicine > Departement Sport, Bewegung und Gesundheit > Bereich Sportwissenschaft > Sport und psychosoziale Gesundheit (Gerber)
03 Faculty of Medicine > Bereich Psychiatrie (Klinik) > Erwachsenenpsychiatrie UPK > Klinische Stress- und Traumaforschung (Holsboer-Trachsler)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Psychiatrie (Klinik) > Erwachsenenpsychiatrie UPK > Klinische Stress- und Traumaforschung (Holsboer-Trachsler)
UniBasel Contributors:Gerber, Markus and Sadeghi Bahmani, Dena and Calabrese, Pasquale and Naegelin, Yvonne and Pühse, Uwe and Holsboer-Trachsler, Edith and Seaward, Helene and Brand, Serge
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Sage
ISSN:0031-5125
e-ISSN:1558-688X
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
Identification Number:
edoc DOI:
Last Modified:21 Jan 2021 04:11
Deposited On:29 Jul 2020 14:03

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