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Matrix-assisted laser desorption/ionization time of flight mass-spectrometry (MALDI-TOF MS) based typing of extended-spectrum beta-lactamase producing E. coli--a novel tool for real-time outbreak investigation

Egli, Adrian and Tschudin-Sutter, Sarah and Oberle, Michael and Goldenberger, Daniel and Frei, Reno and Widmer, Andreas F.. (2015) Matrix-assisted laser desorption/ionization time of flight mass-spectrometry (MALDI-TOF MS) based typing of extended-spectrum beta-lactamase producing E. coli--a novel tool for real-time outbreak investigation. PLoS One, 10 (4). e0120624.

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Official URL: https://edoc.unibas.ch/61722/

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Abstract

Epidemiologically linked clusters are confirmed by typing strains with molecular typing such as pulsed-field gel electrophoresis (PFGE). We compared six extended-spectrum beta-lactamase producing E. coli of a PFGE-related cluster with Matrix-assisted laser desorption/ionization-time of flight mass-spectrometry based typing that confirmed relatedness faster and more cost-effective, but as reliable as PFGE.
Faculties and Departments:03 Faculty of Medicine > Departement Biomedizin > Department of Biomedicine, University Hospital Basel > Applied Microbiology Research (Egli)
UniBasel Contributors:Egli, Adrian
Item Type:Article, refereed
Article Subtype:Research Article
ISSN:1932-6203 (Electronic) 1932-6203 (Linking)
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:20 Oct 2018 09:51
Deposited On:20 Oct 2018 09:51

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