Items where Author is "Gillingwater, K."

2022

Smith, A. and Wall, R. J. and Patterson, S. and Rowan, T. and Rico Vidal, E. and Stojanovski, L. and Huggett, M. and Hampton, S. E. and Thomas, M. G. and Corpas Lopez, V. and Gillingwater, K. and Duke, J. and Napier, G. and Peter, R. and Vitouley, H. S. and Harrison, J. R. and Milne, R. and Jeacock, L. and Baker, N. and Davis, S. H. and Simeons, F. and Riley, J. and Horn, D. and Brun, R. and Zuccotto, F. and Witty, M. J. and Wyllie, S. and Read, K. D. and Gilbert, I. H.. (2022) Repositioning of a diaminothiazole series confirmed to target the cyclin-dependent kinase CRK12 for Use in the TREATMENT of African animal trypanosomiasis. Journal of medicinal chemistry, 65 (7). pp. 5606-5624.

Perieteanu, M. C. and McGee, L. M. C. and Shaw, C. D. and MacMillan, D. S. and Khalaf, A. I. and Gillingwater, K. and Beveridge, R. and Carter, K. C. and Suckling, C. J. and Scott, F. J.. (2022) Selective anti-leishmanial strathclyde minor groove binders using an N-oxide tail-group modification. Int J Mol Sci, 23 (19). p. 11912.

2021

Brooke, D. P. and McGee, L. M. C. and Giordani, F. and Cross, J. M. and Khalaf, A. I. and Irving, C. and Gillingwater, K. and Shaw, C. D. and Carter, K. C. and Barrett, M. P. and Suckling, C. J. and Scott, F. J.. (2021) Correction: Truncated S-MGBs: towards a parasite-specific and low aggregation chemotype. RSC Med Chem, 12 (12). p. 2071.

Brooke, D. P. and McGee, L. M. C. and Giordani, F. and Cross, J. M. and Khalaf, A. I. and Irving, C. and Gillingwater, K. and Shaw, C. D. and Carter, K. C. and Barrett, M. P. and Suckling, C. J. and Scott, F. J.. (2021) Truncated S-MGBs: towards a parasite-specific and low aggregation chemotype. RSC Medicinal Chemistry, 12 (8). pp. 1391-1401.

2020

Singh, B. and Diaz-Gonzalez, R. and Ceballos-Perez, G. and Rojas-Barros, D. I. and Gunaganti, N. and Gillingwater, K. and Martinez-Martinez, M. S. and Manzano, P. and Navarro, M. and Pollastri, M. P.. (2020) Medicinal chemistry optimization of a diaminopurine chemotype: toward a lead for Trypanosoma brucei inhibitors. Journal of medicinal chemistry, 63 (17). pp. 9912-9927.

2019

GIordani, F. and Khalaf, A. I. and Gillingwater, K. and Munday, J. C. and De Koning, H. P. and Suckling, C. J. and Barrett, M. P. and Scott, F. J.. (2019) Novel minor groove binders cure animal african trypanosomiasis in an in vivo mouse model. Journal of medicinal chemistry, 62 (6). pp. 3021-3035.

2018

Gysin, M. and Braissant, O. and Gillingwater, K. and Brun, R. and Mäser, P. and Wenzler, T.. (2018) Isothermal microcalorimetry - a quantitative method to monitor Trypanosoma congolense growth and growth inhibition by trypanocidal drugs in real time. International journal for parasitology. Drugs and drug resistance, 8 (2). pp. 159-164.

2017

Akama, T. and Zhang, Y. K. and Freund, Y. R. and Berry, P. and Lee, J. and Easom, E. E. and Jacobs, R. T. and Plattner, J. J. and Witty, M. J. and Peter, R. and Rowan, T. G. and Gillingwater, K. and Brun, R. and Nare, B. and Mercer, L. and Xu, M. and Wang, J. and Liang, H.. (2017) Identification of a 4-fluorobenzyl L-valinate amide benzoxaborole (AN11736) as a potential development candidate for the treatment of Animal African Trypanosomiasis (AAT). Bioorganic and Medicinal Chemistry Letters, 28. pp. 6-10.

2013

Rogé, S. and Van Reet, N. and Odiwuor, S. and Tran, T. and Schildermans, K. and Vandamme, S. and Vandenberghe, I. and Vervecken, W. and Gillingwater, K. and Claes, F. and Devreese, B. and Guisez, Y. and Büscher, P.. (2013) Recombinant expression of trypanosome surface glycoproteins in Pichia pastoris for the diagnosis of Trypanosoma evansi infection. Veterinary parasitology : an international scientific journal, Vol. 197, H. 3-4. pp. 571-579.

2011

Gillingwater, K. and Gutierrez, C. and Bridges, A. and Wu, H. and Deborggraeve, S. and Ali Ekangu R., and Kumar, A. and Ismail, M. and Boykin, D. and Brun, R.. (2011) Efficacy study of novel diamidine compounds in a Trypanosoma evansi goat model. PLoS ONE, Vol. 6, H. 6 , e20836.

2010

Gillingwater, K. and Kumar, A. and Ismail, M. A. and Arafa, R. K. and Stephens, C. E. and Boykin, D. W. and Tidwell, R. R. and Brun, R.. (2010) In vitro activity and preliminary toxicity of various diamidine compounds against Trypanosoma evansi. Veterinary parasitology : an international scientific journal, Vol. 169. pp. 264-272.

2009

Gillingwater, K. and Kumar, A. and Anbazhagan, M. and Boykin, D. W. and Tidwell, R. R. and Brun, R.. (2009) In vivo investigations of selected diamidine compounds against Trypanosoma evansi using a mouse model. Antimicrobial agents and chemotherapy : AAC, Vol. 53, H. 12. pp. 5074-5079.