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Items where Author is "Fersht, Alan R."

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Arbely, Eyal and Rutherford, Trevor J. and Neuweiler, Hannes and Sharpe, Timothy D. and Ferguson, Neil and Fersht, Alan R.. (2010) Carboxyl pK(a) values and acid denaturation of BBL. Journal of Molecular Biology, 403 (2). pp. 313-327.

Arbely, Eyal and Neuweiler, Hannes and Sharpe, Timothy D. and Johnson, Christopher M. and Fersht, Alan R.. (2010) The human peripheral subunit-binding domain folds rapidly while overcoming repulsive Coulomb forces. Protein Science, 19 (9). pp. 1704-1713.

Arbely, Eyal and Rutherford, Trevor J. and Sharpe, Timothy D. and Ferguson, Neil and Fersht, Alan R.. (2009) Downhill versus barrier-limited folding of BBL 1: energetic and structural perturbation effects upon protonation of a histidine of unusually low pKa. Journal of Molecular Biology, 387 (4). pp. 986-992.

Neuweiler, Hannes and Sharpe, Timothy D. and Johnson, Christopher M. and Teufel, Daniel P. and Ferguson, Neil and Fersht, Alan R.. (2009) Downhill versus barrier-limited folding of BBL 2: mechanistic insights from kinetics of folding monitored by independent tryptophan probes. Journal of Molecular Biology, 387 (4). pp. 975-985.

Neuweiler, Hannes and Sharpe, Timothy D. and Rutherford, Trevor J. and Johnson, Christopher M. and Allen, Mark D. and Ferguson, Neil and Fersht, Alan R.. (2009) The folding mechanism of BBL: Plasticity of transition-state structure observed within an ultrafast folding protein family. Journal of Molecular Biology, 390 (5). pp. 1060-1073.

Sharpe, Timothy D. and Ferguson, Neil and Johnson, Christopher M. and Fersht, Alan R.. (2008) Conservation of transition state structure in fast folding peripheral subunit-binding domains. Journal of Molecular Biology, 383 (1). pp. 224-237.

Huang, Fang and Sato, Satoshi and Sharpe, Timothy D. and Ying, Liming and Fersht, Alan R.. (2007) Distinguishing between cooperative and unimodal downhill protein folding. Proceedings of the National Academy of Sciences of the United States of America, 104 (1). pp. 123-127.

Ferguson, Neil and Sharpe, Timothy D. and Johnson, Christopher M. and Schartau, Pamela J. and Fersht, Alan R.. (2007) Structural biology: analysis of `downhill` protein folding. Nature, 445 (7129). E14-E15.

Sharpe, Tim and Jonsson, Amanda L. and Rutherford, Trevor J. and Daggett, Valerie and Fersht, Alan R.. (2007) The role of the turn in b-hairpin formation during WW domain folding. Protein Science, 1. pp. 2233-2239.

Ferguson, Neil and Becker, Johanna and Tidow, Henning and Tremmel, Sandra and Sharpe, Timothy D. and Krause, Gerd and Flinders, Jeremy and Petrovich, Miriana and Berriman, John and Oschkinat, Hartmut and Fersht, Alan R.. (2006) General structural motifs of amyloid protofilaments. Proceedings of the National Academy of Sciences of the United States of America, 103 (44). pp. 16248-16253.

Ferguson, Neil and Sharpe, Timothy D. and Johnson, Christopher M. and Fersht, Alan R.. (2006) The transition state for folding of a peripheral subunit-binding domain contains robust and ionic-strength dependent characteristics. Journal of Molecular Biology, 356 (5). pp. 1237-1247.

Ferguson, Neil and Sharpe, Timothy D. and Schartau, Pamela J. and Sato, Satoshi and Allen, Mark D. and Johnson, Christopher M. and Rutherford, Trevor J. and Fersht, Alan R.. (2005) Ultra-fast barrier-limited folding in the peripheral subunit-binding domain family. Journal of Molecular Biology, 353 (2). pp. 427-446.

Ferguson, Neil and Schartau, Pamela J. and Sharpe, Timothy D. and Sato, Satoshi and Fersht, Alan R.. (2004) One-state downhill versus conventional protein folding. Journal of Molecular Biology, 344 (2). pp. 295-301.

Ferguson, Neil and Berriman, John and Petrovich, Miriana and Sharpe, Timothy D. and Finch, John T. and Fersht, Alan R.. (2003) Rapid amyloid fiber formation from the fast-folding WW domain FBP28. Proceedings of the National Academy of Sciences of the United States of America, 100 (17). pp. 9814-9819.

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