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A blueprint to address research gaps in the development of biomarkers for pediatric tuberculosis

Nicol, Mark Patrick and Gnanashanmugam, Devasena and Browning, Renee and Click, Eleanor S. and Cuevas, Luis E. and Detjen, Anne and Graham, Steve M. and Levin, Michael and Makhene, Mamodikoe and Nahid, Payam and Perez-Velez, Carlos M. and Reither, Klaus and Song, Rinn and Spiegel, Hans M. L. and Worrell, Carol and Zar, Heather J. and Walzl, Gerhard. (2015) A blueprint to address research gaps in the development of biomarkers for pediatric tuberculosis. Clinical infectious diseases, Vol. 61, H. Suppl. 3 , S164-S172.

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Official URL: http://edoc.unibas.ch/dok/A6438863

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Abstract

Childhood tuberculosis contributes significantly to the global tuberculosis disease burden but remains challenging to diagnose due to inadequate methods of pathogen detection in paucibacillary pediatric samples and lack of a child-specific host biomarker to identify disease. Accurately diagnosing tuberculosis in children is required to improve case detection, surveillance, healthcare delivery, and effective advocacy. In May 2014, the National Institutes of Health convened a workshop including researchers in the field to delineate priorities to address this research gap. This blueprint describes the consensus from the workshop, identifies critical research steps to advance this field, and aims to catalyze efforts toward harmonization and collaboration in this area.
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Medical Parasitology and Infection Biology (MPI) > Tuberculosis Ecology and Evolution Unit (Gagneux)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH)
UniBasel Contributors:Reither, Klaus
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Oxford University Press
ISSN:1058-4838
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:06 Nov 2015 10:21
Deposited On:06 Nov 2015 10:21

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