Fleischkonsum und Serum-Cholesterinkonzentration

In a representative cross-sectional study of the population of Basel, Switzerland (252 men, 281 women, mean age 48 [25-74] years), there was a significant association between the consumption of meat and sausages, determined from a questionnaire, and the total serum cholesterol concentration. In subjects who ate meat or sausages daily, the mean cholesterol concentration was 6.29 mmol/l (242 mg/dl) (95% confidence interval 6.06-6.52 mmol/l) for men, and 6.63 mmol/l (255 mg/dl) (95% confidence interval 6.35-6.91 mmol/l) for women. In subjects who consumed meat or sausages at most once per week, the mean cholesterol concentration was 5.66 mmol/l (218 mg/dl) (95% confidence interval 4.99-6.33 mmol/l) for men, and 5.33 mmol/l (205 mg/dl) (95% confidence interval 4.98-5.68 mmol/l) for women. The association remained significant (P less than 0.001) using multiple linear regression (taking age, sex, social grouping, body mass index and consumption of whole-grain bread, yoghurt or cottage cheese, eggs and alcohol as possible confounding factors). The HDL-cholesterol fraction was not influenced by consumption of meat and sausages. These results support the nutritional advice concerning, among other things, a reduction in the intake of animal fats.