edoc

Correlation of EEG slowing with cognitive domains in nondemented patients with Parkinson's disease

Zimmermann, R. and Gschwandtner, U. and Hatz, F. and Schindler, C. and Bousleiman, H. and Meyer, A. and Calabrese, P. and Fuhr, P.. (2015) Correlation of EEG slowing with cognitive domains in nondemented patients with Parkinson's disease. Dementia and Geriatric Cognitive Disorders, 39 (3-4). pp. 207-214.

[img]
Preview
PDF - Published Version
761Kb

Official URL: http://edoc.unibas.ch/dok/A6357851

Downloads: Statistics Overview

Abstract

Cognitive deficits in Parkinson's disease (PD) are heterogeneous and can be classified into cognitive domains. Quantitative EEG is related to and predictive of cognitive status in PD. In this cross-sectional study, the relationship of cognitive domains and EEG slowing in PD patients without dementia is investigated.; A total of 48 patients with idiopathic PD were neuropsychologically tested. Cognitive domain scores were calculated combining Z-scores of test variables. Slowing of EEG was measured with median EEG frequency. Linear regression was used for correlational analyses and to control for confounding factors.; EEG median frequency was significantly correlated to cognitive performance in most domains (episodic long-term memory, rho = 0.54; overall cognitive score, rho = 0.47; fluency, rho = 0.39; attention, rho = 0.37; executive function, rho = 0.34), but not to visuospatial functions and working memory.; Global EEG slowing is a marker for overall cognitive impairment in PD and correlates with impairment in the domains attention, executive function, verbal fluency, and episodic long-term memory, but not with working memory and visuospatial functions. These disparate effects warrant further investigations.
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Biostatistics > Biostatistics Frequentist Modelling (Kwiatkowski)
UniBasel Contributors:Schindler, Christian and Zimmermann, Ronan and Gschwandtner, Ute and Hatz, Florian and Hardmeier, Martin and Meyer, Antonia and Calabrese, Pasquale and Fuhr, Peter
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Karger
ISSN:1420-8008
e-ISSN:1421-9824
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
Related URLs:
Identification Number:
edoc DOI:
Last Modified:26 Sep 2023 08:32
Deposited On:10 Apr 2015 09:14

Repository Staff Only: item control page