Strelets, V. and Faber, P. L. and Golikova, J. and Novototsky-Vlasov, V. and Koenig, T. and Gianotti, L. R. R. and Gruzelier, J. H. and Lehmann, D.. (2003) Chronic schizophrenics with positive symptomatology have shortened EEG microstate durations. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, Vol. 114, H. 11. pp. 2043-2051.
![]() |
PDF
Restricted to Repository staff only 167Kb |
Official URL: http://edoc.unibas.ch/dok/A5844632
Downloads: Statistics Overview
Abstract
In young, first-episode, never-treated schizophrenics compared with controls, (a) generally shorter durations of EEG microstates were reported (Koukkou et al., Brain Topogr 6 (1994) 251; Kinoshita et al., Psychiatry Res Neuroimaging 83 (1998) 58), and (b) specifically, shorter duration of a particular class of microstates (Koenig et al., Eur Arch Psychiatry Clin Neurosci 249 (1999) 205). We now examined whether older, chronic schizophrenic patients with positive symptomatology also show these characteristics.; Multichannel resting EEG (62.2 s/subject) from two subject groups, 14 patients (36.1+/-10.2 years old) and 13 controls (35.1+/-8.2 years old), all males, was analyzed into microstates using a global approach for microstate analysis that clustered the microstates into 4 classes (Koenig et al., 1999).; (a) Hypothesis testing of general microstate shortening supported a trend (P=0.064). (b) Two-way repeated measure ANOVA (two subject groupsx4 microstate classes) showed a significant group effect for microstate duration. Posthoc tests revealed that a microstate class with brain electric field orientation from left central to right central-posterior had significantly shorter microstates in patients than controls (68.5 vs. 76.1 ms, P=0.034).; The results were in line with the results from young, never-treated, productive patients, thus suggesting that in schizophrenic information processing, one class of mental operations might intermittently cause deviant mental constructs because of premature termination of processing.
UniBasel Contributors: | Gianotti, Lorena R. R. |
---|---|
Item Type: | Article, refereed |
Article Subtype: | Research Article |
Publisher: | Elsevier |
ISSN: | 1388-2457 |
Note: | Publication type according to Uni Basel Research Database: Journal article |
Language: | English |
Related URLs: | |
Identification Number: |
|
edoc DOI: | |
Last Modified: | 31 Dec 2015 10:49 |
Deposited On: | 14 Sep 2012 06:51 |
Repository Staff Only: item control page