Bonhoeffer, J. and Baer, G. and Muehleisen, B. and Aebi, C. and Nadal, D. and Schaad, U. B. and Heininger, U.. (2005) Prospective surveillance of hospitalisations associated with varicella-zoster virus infections in children and adolescents. European journal of pediatrics, Vol. 164, H. 6. pp. 366-370.
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Official URL: http://edoc.unibas.ch/dok/A5838831
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Abstract
Our goal was to determine the epidemiology of severe varicella-zoster virus (VZV) infections in hospitalised paediatric patients. Admissions associated with VZV infection of patients aged 0-16 years were reported by all 38 paediatric units in Switzerland to the Swiss Paediatric Surveillance Unit (SPSU) during 3 consecutive years (4/2000-3/2003). We verified completeness of reporting by capture-recapture analysis with patient records identified by ICD-10 codes. Outcome of illness was assessed 6 months after hospitalisation. A total of 335 cases (235 identified by SPSU reports, 100 by ICD-10 code) were included in this study. Mean age of patients was 4.1 years (median 3.5 years, range 0-16 years); 54 chickenpox, 42 (13 not immunocompromised. A total of 319 complications occurred in 237 (71 nervous system involvement (n = 76); VZV pneumonitis (n = 7); others (n = 127). Eleven (3 On follow-up, 303 (96 sequelae were present in 12 (4 hospitalisation rate was 13 per 104 cases. Conclusion: This study describes a sizeable hospitalisation and complication rate of varicella-zoster virus infections and provides a solid basis for future immunisation recommendations in Switzerland.
Faculties and Departments: | 03 Faculty of Medicine > Bereich Kinder- und Jugendheilkunde (Klinik) > Kinder- und Jugendheilkunde (UKBB) 03 Faculty of Medicine > Departement Klinische Forschung > Bereich Kinder- und Jugendheilkunde (Klinik) > Kinder- und Jugendheilkunde (UKBB) 03 Faculty of Medicine |
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UniBasel Contributors: | Heininger, Ulrich |
Item Type: | Article, refereed |
Article Subtype: | Research Article |
Publisher: | Springer |
ISSN: | 1432-1076 |
Note: | Publication type according to Uni Basel Research Database: Journal article |
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Identification Number: |
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Last Modified: | 08 Jun 2012 06:53 |
Deposited On: | 08 Jun 2012 06:29 |
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