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Autism symptoms in Attention-Deficit/Hyperactivity Disorder: a familial trait which correlates with conduct, oppositional defiant, language and motor disorders

Mulligan, Aisling and Anney, Richard J. L. and O'Regan, Myra and Chen, Wai and Butler, Louise and Fitzgerald, Michael and Buitelaar, Jan and Steinhausen, Hans-Christoph and Rothenberger, Aribert and Minderaa, Ruud and Nijmeijer, Judith and Hoekstra, Pieter J. and Oades, Robert D. and Roeyers, Herbert and Buschgens, Cathelijne and Christiansen, Hanna and Franke, Barbara and Gabriels, Isabel and Hartman, Catharina and Kuntsi, Jonna and Marco, Rafaela and Meidad, Sheera and Mueller, Ueli and Psychogiou, Lamprini and Rommelse, Nanda and Thompson, Margaret and Uebel, Henrik and Banaschewski, Tobias and Ebstein, Richard and Eisenberg, Jacques and Manor, Iris and Miranda, Ana and Mulas, Fernando and Sergeant, Joseph and Sonuga-Barke, Edmund and Asherson, Phil and Faraone, Stephen V. and Gill, Michael. (2009) Autism symptoms in Attention-Deficit/Hyperactivity Disorder: a familial trait which correlates with conduct, oppositional defiant, language and motor disorders. Journal of autism and developmental disorders, 39 (2). pp. 197-209.

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Official URL: http://edoc.unibas.ch/dok/A5250674

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Abstract

It is hypothesised that autism symptoms are present in Attention-Deficit/Hyperactivity Disorder (ADHD), are familial and index subtypes of ADHD. Autism symptoms were compared in 821 ADHD probands, 1050 siblings and 149 controls. Shared familiality of autism symptoms and ADHD was calculated using DeFries-Fulker analysis. Autism symptoms were higher in probands than siblings or controls, and higher in male siblings than male controls. Autism symptoms were familial, partly shared with familiality of ADHD in males. Latent class analysis using SCQ-score yielded five classes; Class 1(31%) had few autism symptoms and low comorbidity; Classes 2-4 were intermediate; Class 5(7%) had high autism symptoms and comorbidity. Thus autism symptoms in ADHD represent a familial trait associated with increased neurodevelopmental and oppositional/conduct disorders.
Faculties and Departments:07 Faculty of Psychology > Departement Psychologie > Ehemalige Einheiten Psychologie > Clinical Child and Adolescent Psychology (Schneider)
07 Faculty of Psychology > Departement Psychologie > Health & Intervention > Klinische Psychologie und Epidemiologie (Lieb)
UniBasel Contributors:Steinhausen, Hans-Christoph
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Kluwer
ISSN:0162-3257
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:06 Jul 2021 06:49
Deposited On:22 Mar 2012 13:42

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