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Rhinitis in Swiss adults is associated with asthma and early life factors, but not second hand tobacco smoke or obesity

Abramson, Michael J. and Schindler, Christian and Schikowski, Tamara and Bircher, Andreas J. and Burdet, Luc and Gerbase, Margaret W. and Imboden, Medea and Rochat, Thierry and Schmid-Grendelmeier, Peter and Turk, Alexander J. and Zemp, Elisabeth and Künzli, Nino and Probst-Hensch, Nicole. (2016) Rhinitis in Swiss adults is associated with asthma and early life factors, but not second hand tobacco smoke or obesity. Allergology international, 65 (2). pp. 192-198.

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Official URL: http://edoc.unibas.ch/44208/

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Abstract

Second hand tobacco smoke (SHS) and overweight/obesity are risk factors for asthma and lower airway respiratory symptoms. We investigated whether SHS or overweight/obesity were also associated with allergic or non-allergic rhinitis.; Cross-sectional data were obtained during the second SAPALDIA Study. Interviewer administered questionnaires were completed by 8047 participants from 8 communities in Switzerland. Blood was collected from 5841 participants and tested for allergen specific IgE. Allergic rhinitis was defined as nasal symptoms with detectable IgE. Data were analysed by multinomial logistic regression with four outcome categories defined according to the presence or absence of rhinitis and/or atopy.; The prevalence of allergic rhinitis was 885 (15.2%) and non-allergic rhinitis 323 (5.5%). The risk of allergic rhinitis was increased in subjects with physician diagnosed asthma (Relative Risk Ratio 6.81; 95%CI 5.39, 8.6), maternal atopy (1.56; 1.27, 1.92) and paternal atopy (1.41; 1.11, 1.79). Older subjects were at lower risk (0.96; 0.95,0.97 per year), as were those raised on a farm (0.64; 0.49,0.84), with older siblings (0.92; 0.86,0.97 per sib) or from rural areas. The risk of non-allergic rhinitis was also increased in subjects with physician diagnosed asthma (4.02; 2.86, 5.67), reduced in males (0.59; 0.46, 0.77), but not associated with upbringing on a farm or older siblings. There were no significant associations of SHS or overweight/obesity with either form of rhinitis.; Allergic and non-allergic rhinitis have different risk factors apart from asthma. There are significant regional variations within Switzerland, which are not explained by the factors examined.
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Biostatistics > Biostatistics - Frequency Modelling (Schindler)
UniBasel Contributors:Künzli, Nino and Schindler, Christian and Probst Hensch, Nicole and Imboden, Medea and Schikowski, Tamara and Zemp Stutz, Elisabeth
Item Type:Article, refereed
Publisher:The Japanese Society of Allergology
ISSN:1323-8930
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:27 Oct 2016 14:05
Deposited On:27 Oct 2016 14:05

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