edoc

Alcohol use and depression: link with adherence and viral suppression in adult patients on antiretroviral therapy in rural Lesotho, Southern Africa: a cross-sectional study

Cerutti, Bernard and Broers, Barbara and Masetsibi, Motlomelo and Faturiyele, Olatunbosun and Toti-Mokoteli, Likabelo and Motlatsi, Mokete and Bader, Joelle and Klimkait, Thomas and Labhardt, Niklaus D.. (2016) Alcohol use and depression: link with adherence and viral suppression in adult patients on antiretroviral therapy in rural Lesotho, Southern Africa: a cross-sectional study. BMC Public Health, 16. p. 947.

[img] PDF - Published Version
Available under License CC BY (Attribution).

445Kb

Official URL: http://edoc.unibas.ch/44187/

Downloads: Statistics Overview

Abstract

BACKGROUND: Depression and alcohol use disorder have been shown to be associated with poor adherence to antiretroviral therapy (ART). Studies examining their association with viral suppression in rural Africa are, however, scarce.
METHODS: This study reports prevalence of depressive symptoms and alcohol use disorder, and their potential association with adherence and viral suppression in adult patients on ART in ten clinics in rural Lesotho, Southern Africa.
RESULTS: Among 1,388 adult patients (69 % women), 80.7 % were alcohol abstinent, 6.3 % were hazardous drinkers (men: 10.7 %, women: 4.4 %, p < 0.001). The prevalence of depressive symptoms was 28.8 % (men 20.2 %, women 32.7 %, p < 0.001). Both alcohol consumption (adjusted odds-ratio: 2.09, 95 % CI: 1.58-2.77) and alcohol use disorder (2.73, 95 % CI: 1.68-4.42) were significantly associated with poor adherence. There was, however, no significant association with viral suppression.
CONCLUSIONS: Whereas the results of this study confirm previously reported association of alcohol use disorder with adherence to ART, there was no association with viral suppression.
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH)
UniBasel Contributors:Labhardt, Niklaus
Item Type:Article, refereed
Publisher:BioMed Central
e-ISSN:1471-2458
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
Identification Number:
Last Modified:04 Oct 2016 15:07
Deposited On:04 Oct 2016 15:07

Repository Staff Only: item control page