Items where Author is "Siccardi, Marco"

2021

Stader, Felix and Courlet, Perrine and Kinvig, Hannah and Penny, Melissa A. and Decosterd, Laurent A. and Battegay, Manuel and Siccardi, Marco and Marzolini, Catia. (2021) Clinical Data Combined With Modeling and Simulation Indicate Unchanged Drug-Drug Interaction Magnitudes in the Elderly. Clinical Pharmacology & Therapeutics, 109 (2). pp. 471-484.

Stader, Felix and Courlet, Perrine and Kinvig, Hannah and Battegay, Manuel and Decosterd, Laurent A. and Penny, Melissa A. and Siccardi, Marco and Marzolini, Catia. (2021) Effect of ageing on antiretroviral drug pharmacokinetics using clinical data combined with modelling and simulation. British Journal of Clinical Pharmacology, 87 (2). pp. 458-470.

2020

Hodge, Catherine and Marra, Fiona and Marzolini, Catia and Boyle, Alison and Gibbons, Sara and Siccardi, Marco and Burger, David and Back, David and Khoo, Saye. (2020) Drug interactions: a review of the unseen danger of experimental COVID-19 therapies. The journal of antimicrobial chemotherapy, 75 (12). pp. 3417-3424.

2019

Stader, Felix and Penny, Melissa A. and Siccardi, Marco and Marzolini, Catia. (2019) A comprehensive framework for physiologically based pharmacokinetic modelling in Matlab. CPT: Pharmacometrics and Systems Pharmacology, 8 (7). pp. 444-459.

Stader, Felix and Kinvig, Hannah and Penny, Melissa A. and Battegay, Manuel and Siccardi, Marco and Marzolini, Catia. (2019) Physiologically Based Pharmacokinetic Modelling to Identify Pharmacokinetic Parameters Driving Drug Exposure Changes in the Elderly. Clinical pharmacokinetics, 59 (3). pp. 383-401.

2018

Stader, Felix and Kinvig, Hannah and Battegay, Manuel and Khoo, Saye and Owen, Andrew and Siccardi, Marco and Marzolini, Catia. (2018) Analysis of Clinical Drug-Drug Interaction Data To Predict Magnitudes of Uncharacterized Interactions between Antiretroviral Drugs and Comedications. Antimicrobial Agents and Chemotherapy, 62 (7). e00717-18.

Stader, Felix and Siccardi, Marco and Battegay, Manuel and Kinvig, Hannah and Penny, Melissa A. and Marzolini, Catia. (2018) Repository Describing an Aging Population to Inform Physiologically Based Pharmacokinetic Models Considering Anatomical, Physiological, and Biological Age-Dependent Changes. Clinical pharmacokinetics. NA.

2017

Marzolini, Catia and Rajoli, Rajith and Battegay, Manuel and Elzi, Luigia and Back, David and Siccardi, Marco. (2017) Physiologically Based Pharmacokinetic Modeling to Predict Drug-Drug Interactions with Efavirenz Involving Simultaneous Inducing and Inhibitory Effects on Cytochromes. Clinical Pharmacokinetics, 56 (4). pp. 409-420.

2015

Moss, Darren Michael and Marzolini, Catia and Rajoli, Rajith K. R. and Siccardi, Marco. (2015) Applications of physiologically based pharmacokinetic modeling for the optimization of anti-infective therapies. Expert Opinion on Drug Metabolism & Toxicology, 11 (8). pp. 1203-1217.

Marzolini, Catia and Sabin, Caroline and Raffi, François and Siccardi, Marco and Mussini, Cristina and Launay, Odile and Burger, David and Roca, Bernardino and Fehr, Jan and Bonora, Stefano and Mocroft, Amanda and Obel, Niels and Dauchy, Frederic-Antoine and Zangerle, Robert and Gogos, Charalambos and Gianotti, Nicola and Ammassari, Adriana and Torti, Carlo and Ghosn, Jade and Chêne, Genevieve and Grarup, Jesper and Battegay, Manuel. (2015) Impact of body weight on virological and immunological responses to efavirenz-containing regimens in HIV-infected, treatment-naive adults. AIDS (London, England), 29 (2). pp. 193-200.

2013

Siccardi, Marco and Marzolini, Catia and Seden, Kay and Almond, Lisa and Kirov, Anna and Khoo, Saye and Owen, Andrew and Back, David. (2013) Prediction of drug-drug interactions between various antidepressants and efavirenz or boosted protease inhibitors using a physiologically based pharmacokinetic modelling approach. Clinical Pharmacokinetics, 52 (7). pp. 583-592.

2012

de Roche, Mirjam and Siccardi, Marco and Stoeckle, Marcel and Livio, Françoise and Back, David and Battegay, Manuel and Marzolini, Catia. (2012) Efavirenz in an obese HIV-infected patient - a report and an in vitro-in vivo extrapolation model indicate risk of underdosing. Antiviral Therapy, 17 (7). pp. 1381-1384.

Siccardi, Marco and Almond, Lisa and Schipani, Alessandro and Csajka, Chantal and Marzolini, Catia and Wyen, C. and Brockmeyer, Norbert H. and Boffito, M. and Owen, Andrew and Back, David. (2012) Pharmacokinetic and pharmacodynamic analysis of efavirenz dose reduction using an in vitro-in vivo extrapolation model. Clinical Pharmacology and Therapeutics, 92 (4). pp. 494-502.