Items where Author is "Hao-Shen, Hui"

2019

Nageswara Rao, Tata and Hansen, Nils and Hilfiker, Julian and Rai, Shivam and Majewska, Julia-Magdalena and Lekovic, Danijela and Gezer, Deniz and Andina, Nicola and Galli, Serena and Cassel, Teresa and Geier, Florian and Delezie, Julien and Nienhold, Ronny and Hao-Shen, Hui and Beisel, Christian and Di Palma, Serena and Dimeloe, Sarah and Trebicka, Jonel and Wolf, Dominik and Gassmann, Max and Fan, Teresa W.-M. and Lane, Andrew N. and Handschin, Christoph and Dirnhofer, Stefan and Kröger, Nicolaus and Hess, Christoph and Radimerski, Thomas and Koschmieder, Steffen and Cokic, Vladan P. and Skoda, Radek C.. (2019) JAK2 mutant hematopoietic cells display metabolic alterations that can be targeted to treat myeloproliferative neoplasms. Blood, 134 (21). pp. 1832-1846.

2016

Grisouard, Jean and Li, Sai and Kubovcakova, Lucia and Rao, Tata Nageswara and Meyer, Sara C. and Lundberg, Pontus and Hao-Shen, Hui and Romanet, Vincent and Murakami, Masato and Radimerski, Thomas and Dirnhofer, Stephan and Skoda, Radek C.. (2016) JAK2 exon 12 mutant mice display isolated erythrocytosis and changes in iron metabolism favoring increased erythropoiesis. Blood, 128 (6). pp. 839-851.

2015

Grisouard, Jean and Shimizu, Takafumi and Duek, Adrian and Kubovcakova, Lucia and Hao-Shen, Hui and Dirnhofer, Stephan and Skoda, Radek C.. (2015) Deletion of Stat3 in hematopoietic cells enhances thrombocytosis and shortens survival in a JAK2-V617F mouse model of MPN. Blood, 125 (13). pp. 2131-2140.

2014

Lundberg, Pontus and Karow, Axel and Nienhold, Ronny and Looser, Renate and Hao-Shen, Hui and Nissen, Ina and Girsberger, Sabine and Lehmann, Thomas and Passweg, Jakob and Stern, Martin and Beisel, Christian and Kralovics, Robert and Skoda, Radek C.. (2014) Clonal evolution and clinical correlates of somatic mutations in myeloproliferative neoplasms. Blood, 123 (14). pp. 2220-2228.

Duek, Adrian and Lundberg, Pontus and Shimizu, Takafumi and Grisouard, Jean and Karow, Axel and Kubovcakova, Lucia and Hao-Shen, Hui and Dirnhofer, Stephan and Skoda, Radek C.. (2014) Loss of Stat1 decreases megakaryopoiesis and favors erythropoiesis in a JAK2-V617F-driven mouse model of MPNs. Blood, 123 (25). pp. 3943-3950.

Lundberg, Pontus and Takizawa, Hitoshi and Kubovcakova, Lucia and Guo, Guoji and Hao-Shen, Hui and Dirnhofer, Stephan and Orkin, Stuart H. and Manz, Markus G. and Skoda, Radek C.. (2014) Myeloproliferative neoplasms can be initiated from a single hematopoietic stem cell expressing JAK2-V617F. Journal of experimental medicine, 211 (11). pp. 2213-2230.

Grisouard, Jean and Hao-Shen, Hui and Dirnhofer, Stefan and Wagner, Kay-Uwe and Skoda, Radek C.. (2014) Selective deletion of Jak2 in adult mouse hematopoietic cells leads to lethal anemia and thrombocytopenia. Haematologica, 99 (4). e52-4.

2011

Schaub, Franz X. and Lehmann, Thomas and Looser, Renate and Hao-Shen, Hui and Tichelli, Andre and Skoda, Radek C.. (2011) Transition to homozygosity does not appear to provide a clonal advantage to hematopoietic progenitors carrying mutations in TET2. Blood, Vol. 117, H. 6. pp. 2075-2076.

2010

Schaub, Franz X. and Looser, Renate and Li, Sai and Hao-Shen, Hui and Lehmann, Thomas and Tichelli, Andre and Skoda, Radek C.. (2010) Clonal analysis of TET2 and JAK2 mutations suggests that TET2 can be a late event in the progression of myeloproliferative neoplasms. Blood, Vol. 115, H. 10. pp. 2003-2007.

2009

Schaub, Franz X. and Jäger, Roland and Looser, Renate and Hao-Shen, Hui and Hermouet, Sylvie and Girodon, François and Tichelli, Andre and Gisslinger, Heinz and Kralovics, Robert and Skoda, Radek C.. (2009) Clonal analysis of deletions on chromosome 20q and JAK2-V617F in MPD suggests that del20q acts independently and is not one of the predisposing mutations for JAK2-V617F. Blood : the journal of the American Society of Hematology, Vol. 113. pp. 2022-2027.

Tiedt, Ralph and Coers, Jörn and Ziegler, Sandra and Wiestner, Adrian and Hao-Shen, Hui and Bornmann, Caroline and Schenkel, Johannes and Karakhanova, Svetlana and de Sauvage, Frederic J. and Jackson, Carl W. and Skoda, Radek C.. (2009) Pronounced thrombocytosis in transgenic mice expressing reduced levels of Mpl in platelets and terminally differentiated megakaryocytes. Blood : the journal of the American Society of Hematology, Vol. 113. pp. 1768-1777.

2008

Tiedt, Ralph and Hao-Shen, Hui and Sobas, Marta A. and Looser, Renate and Dirnhofer, Stephan and Schwaller, Jürg and Skoda, Radek C.. (2008) Ratio of mutant JAK2-V617F to wild-type Jak2 determines the MPD phenotypes in transgenic mice. Blood, 111 (8). pp. 3931-3940.

Theocharides, Alexandre and Passweg, Jakob R. and Medinger, Michael and Looser, Renate and Li, Sai and Hao-Shen, Hui and Buser, Andreas S. and Gratwohl, Alois and Tichelli, André and Skoda, Radek C.. (2008) The allele burden of JAK2 mutations remains stable over several years in patients with myeloproliferative disorders. Haematologica, 93 (12). pp. 1890-1893.