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Items where Author is "Diederich, François"

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Number of items: 17.

2019

De Gasparo, Raoul and Halgas, Ondrej and Harangozo, Dora and Kaiser, Marcel and Pai, Emil F. and Krauth-Siegel, R. Luise and Diederich, François. (2019) Targeting a large active site : structure-based design of nanomolar inhibitors of Trypanosoma brucei trypanothione reductase. Chemistry - A European Journal, 25 (49). pp. 11416-11421.

2018

Giroud, Maude and Kuhn, Bernd and Saint-Auret, Sarah and Kuratli, Christoph and Martin, Rainer E. and Schuler, Franz and Diederich, François and Kaiser, Marcel and Brun, Reto and Schirmeister, Tanja and Haap, Wolfgang. (2018) 2 H-1,2,3-Triazole-based dipeptidyl nitriles : potent, selective, and Trypanocidal rhodesain inhibitors by structure-based design. Journal of medicinal chemistry, 61 (8). pp. 3370-3388.

De Gasparo, Raoul and Brodbeck-Persch, Elke and Bryson, Steve and Hentzen, Nina B. and Kaiser, Marcel and Pai, Emil F. and Krauth-Siegel, R. Luise and Diederich, François. (2018) Biological evaluation and x-ray co-crystal structures of cyclohexylpyrrolidine ligands for trypanothione reductase, an enzyme from the redox metabolism of trypanosoma. ChemMedChem, 13 (9). pp. 957-967.

Schwertz, Geoffrey and Witschel, Matthias C. and Rottmann, Matthias and Leartsakulpanich, Ubolsree and Chitnumsub, Penchit and Jaruwat, Aritsara and Amornwatcharapong, Watcharee and Ittarat, Wanwipa and Schäfer, Anja and Aponte, Raphael A. and Trapp, Nils and Chaiyen, Pimchai and Diederich, François. (2018) Potent inhibitors of plasmodial serine hydroxymethyltransferase (SHMT) featuring a spirocyclic scaffold. ChemMedChem, 13 (9). pp. 931-943.

Giroud, Maude and Dietzel, Uwe and Anselm, Lilli and Banner, David and Kuglstatter, Andreas and Benz, Jörg and Blanc, Jean-Baptiste and Gaufreteau, Delphine and Liu, Haixia and Lin, Xianfeng and Stich, August and Kuhn, Bernd and Schuler, Franz and Kaiser, Marcel and Brun, Reto and Schirmeister, Tanja and Kisker, Caroline and Diederich, François and Haap, Wolfgang. (2018) Repurposing a library of human cathepsin L ligands : identification of macrocyclic lactams as potent rhodesain and Trypanosoma brucei inhibitors. Journal of medicinal chemistry, 61 (8). pp. 3350-3369.

2017

Schwertz, Geoffrey and Witschel, Matthias C. and Rottmann, Matthias and Bonnert, Roger and Leartsakulpanich, Ubolsree and Chitnumsub, Penchit and Jaruwat, Aritsara and Ittarat, Wanwipa and Schäfer, Anja and Aponte, Raphael A. and Charman, Susan A. and White, Karen L. and Kundu, Abhijit and Sadhukhan, Surajit and Lloyd, Mel and Freiberg, Gail M. and Srikumaran, Myron and Siggel, Marc and Zwyssig, Adrian and Chaiyen, Pimchai and Diederich, François. (2017) Antimalarial inhibitors rargeting serine hydroxymethyltransferase (SHMT) with in vivo efficacy and analysis of their binding mode based on X-ray cocrystal structures. Journal of Medicinal Chemistry, 60 (12). pp. 4840-4860.

Schwertz, Geoffrey and Frei, Michelle S. and Witschel, Matthias C. and Rottmann, Matthias and Leartsakulpanich, Ubolsree and Chitnumsub, Penchit and Jaruwat, Aritsara and Ittarat, Wanwipa and Schäfer, Anja and Aponte, Raphael A. and Trapp, Nils and Mark, Kerstin and Chaiyen, Pimchai and Diederich, François. (2017) Conformational aspects in the design of inhibitors for serine hydroxymethyltransferase (SHMT): biphenyl, aryl sulfonamide, and aryl sulfone motifs. Chemistry - A European Journal, 23 (57). pp. 14345-14357.

2016

Milic, Jovana and Zalibera, Michal and Pochorovski, Igor and Trapp, Nils and Nomrowski, Julia and Neshchadin, Dmytro and Ruhlmann, Laurent and Boudon, Corinne and Wenger, Oliver S. and Savitsky, Anton and Lubitz, Wolfgang and Gescheit, Georg and Diederich, François. (2016) Paramagnetic Molecular Grippers: The Elements of Six-State Redox Switches. Journal of Physical Chemistry Letters, 7 (13). pp. 2470-2477.

2015

Witschel, Matthias C. and Rottmann, Matthias and Schwab, Anatol and Leartsakulpanich, Ubolsree and Chitnumsub, Penchit and Seet, Michael and Tonazzi, Sandro and Schwertz, Geoffrey and Stelzer, Frank and Mietzner, Thomas and McNamara, Case and Thater, Frank and Freymond, Céline and Jaruwat, Aritsara and Pinthong, Chatchadaporn and Riangrungroj, Pinpunya and Oufir, Mouhssin and Hamburger, Matthias and Mäser, Pascal and Sanz-Alonso, Laura M. and Charman, Susan and Wittlin, Sergio and Yuthavong, Yongyuth and Chaiyen, Pimchai and Diederich, François. (2015) Inhibitors of plasmodial serine hydroxymethyltransferase (SHMT) : co-crystal structures of pyrazolopyrans with potent blood-and liver-stage activities. Journal of Medicinal Chemistry, 58 (7). pp. 3117-3130.

2014

Persch, Elke and Bryson, Steve and Todoroff, Nickolay K. and Eberle, Christian and Thelemann, Jonas and Dirdjaja, Natalie and Kaiser, Marcel and Weber, Maria and Derbani, Hassan and Brun, Reto and Schneider, Gisbert and Pai, Emil F. and Krauth-Siegel, R. Luise and Diederich, François. (2014) Binding to large enzyme pockets : small-molecule inhibitors of trypanothione reductase. ChemMedChem, Vol. 9, H. 8. pp. 1880-1891.

Reker, Daniel and Seet, Michael and Pillong, Max and Koch, Christian P. and Schneider, Petra and Witschel, Matthias C. and Rottmann, Matthias and Freymond, Céline and Brun, Reto and Schweizer, Bernd and Illarionov, Boris and Bacher, Adelbert and Fischer, Markus and Diederich, François and Schneider, Gisbert. (2014) Deorphaning pyrrolopyrazines as potent multi-target antimalarial agents. Angewandte Chemie, Jg. 53, Nr. 27. pp. 7079-7084.

Kunfermann, Andrea and Witschel, Matthias and Illarionov, Boris and Martin, René and Rottmann, Matthias and Höffken, H. Wolfgang and Seet, Michael and Eisenreich, Wolfgang and Knölker, Hans-Joachim and Fischer, Markus and Bacher, Adelbert and Groll, Michael and Diederich, François. (2014) Pseudilins : halogenated, allosteric inhibitors of the non-mevalonate pathway enzyme IspD. Angewandte Chemie. International edition in English, Vol. 53, H. 8. pp. 2235-2239.

2013

Shchyrba, Aneliia and Nguyen, Manh-Thuong and Wäckerlin, Christian and Martens, Susanne and Nowakowska, Sylwia and Ivas, Toni and Roose, Jesse and Nijs, Thomas and Boz, Serpil and Schär, Michael and Stöhr, Meike and Pignedoli, Carlo A. and Thilgen, Carlo and Diederich, François and Passerone, Daniele and Jung, Thomas A.. (2013) Chirality transfer in 1D self-assemblies: influence of H-bonding vs metal coordination between dicyano[7]helicene enantiomers. Journal of the American Chemical Society, 135 (41). pp. 15270-15273.

Ehmke, Veronika and Winkler, Edwin and Banner, David W. and Haap, Wolfgang and Schweizer, W. Bernd and Rottmann, Matthias and Kaiser, Marcel and Freymond, Céline and Schirmeister, Tanja and Diederich, François. (2013) Optimization of triazine nitriles as rhodesain inhibitors : structure-activity relationships, bioisosteric imidazopyridine nitriles, and X-ray crystal structure analysis with human cathepsin L. ChemMedChem : chemistry enabling drug discovery, Vol. 8, H. 6. pp. 967-975.

2012

Iacovita, Cristian and Fesser, Petra and Vijayaraghavan, Saranyan and Enache, Mihaela and Stöhr, Meike and Diederich, François and Jung, Thomas A.. (2012) Controlling the Dimensionality and Structure of Supramolecular Porphyrin Assemblies by their Functional Substituents: Dimers, Chains, and Close-Packed 2D Assemblies. Chemistry - A European Journal, 18 (46). pp. 14610-14613.

2011

Stöhr, Meike and Boz, Serpil and Schär, Michael and Nguyen, Manh-Thuong and Pignedoli, Carlo A. and Passerone, Daniele and Schweizer, W. Bernd and Thilgen, Carlo and Jung, Thomas A. and Diederich, François. (2011) Self-assembly and two-dimensional spontaneous resolution of cyano-functionalized [7]helicenes on Cu111. Angewandte Chemie International Edition, 50 (42). pp. 9982-9986.

Fesser, Petra and Iacovita, Cristian and Wäckerlin, Christian and Vijayaraghavan, Saranyan and Ballav, Nirmalya and Howes, Kara and Gisselbrecht, Jean-Paul and Crobu, Maura and Boudon, Corinne and Stöhr, Meike and Jung, Thomas A. and Diederich, François. (2011) Visualizing the product of a formal cycloaddition of 7,7,8,8-tetracyano-p-quinodimethane (TCNQ) to an acetylene-appended porphyrin by scanning tunneling microscopy on Au(111). Chemistry - A European Journal, 17 (19). pp. 5246-5250.

This list was generated on Thu Nov 14 19:01:16 2019 CET.