Items where Author is "Brault, Laurent"

2016

Stavropoulou, Vaia and Kaspar, Susanne and Brault, Laurent and Sanders, Mathijs A. and Juge, Sabine and Morettini, Stefano and Tzankov, Alexandar and Iacovino, Michelina and Lau, I-Jun and Milne, Thomas A. and Royo, Hélène and Kyba, Michael and Valk, Peter J. M. and Peters, Antoine H. F. M. and Schwaller, Juerg. (2016) MLL-AF9 Expression in Hematopoietic Stem Cells Drives a Highly Invasive AML Expressing EMT-Related Genes Linked to Poor Outcome. Cancer cell, 30 (1). pp. 43-58.

2012

Huber, Kilian and Brault, Laurent and Fedorov, Oleg and Gasser, Christelle and Filippakopoulos, Panagis and Bullock, Alex N. and Fabbro, Doriano and Trappe, Jörg and Schwaller, Jürg and Knapp, Stefan and Bracher, Franz. (2012) 7,8-dichloro-1-oxo-β-carbolines as a versatile scaffold for the development of potent and selective kinase inhibitors with unusual binding modes. Journal of Medicinal Chemistry, 55 (1). pp. 403-413.

Brault, Laurent and Menter, Thomas and Obermann, Ellen C. and Knapp, Stefan and Thommen, Sarah and Schwaller, Jürg and Tzankov, Alexandar. (2012) PIM kinases are progression markers and emerging therapeutic targets in diffuse large B-cell lymphoma. British journal of cancer, 107 (3). pp. 491-500.

2011

Miduturu, Chandrasekhar V. and Deng, Xianming and Kwiatkowski, Nicholas and Yang, Wannian and Brault, Laurent and Filippakopoulos, Panagis and Chung, Eunah and Yang, Qingkai and Schwaller, Juerg and Knapp, Stefan and King, Randall W. and Lee, Jiing-Dwan and Herrgard, Sanna and Zarrinkar, Patrick and Gray, Nathanael S.. (2011) High-throughput kinase profiling : a more efficient approach toward the discovery of new kinase inhibitors. Chemistry & biology, Vol. 18, H. 7. pp. 868-879.

2010

Stavropoulou, Vaia and Brault, Laurent and Schwaller, Juerg. (2010) Insights into molecular pathways for targeted therapeutics in acute leukemia. Swiss medical weekly, Vol. 140 , w13068.

Brault, Laurent and Gasser, Christelle and Bracher, Franz and Huber, Kilian and Knapp, Stefan and Schwaller, Jürg. (2010) PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers. Haematologica, Vol. 95, H. 6. pp. 1004-1015.

2009

Grundler, Rebekka and Brault, Laurent and Gasser, Christelle and Bullock, Alex N. and Dechow, Tobias and Woetzel, Sabine and Pogacic, Vanda and Villa, Antonello and Ehret, Sabine and Berridge, Georgina and Spoo, Anke and Dierks, Christine and Biondi, Andrea and Knapp, Stefan and Duyster, Justus and Schwaller, Juerg. (2009) Dissection of PIM serine/threonine kinases in FLT3-ITD-induced leukemogenesis reveals PIM1 as regulator of CXCL12-CXCR4-mediated homing and migration. Journal of Experimental Medicine, 206 (9). pp. 1957-1970.