Items where Author is "Altmann, Karl-Heinz"

2020

Warryn, Louisa and Dangy, Jean-Pierre and Gersbach, Philipp and Gehringer, Matthias and Schäfer, Anja and Ruf, Marie-Thérèse and Ruggli, Nicolas and Altmann, Karl-Heinz and Pluschke, Gerd. (2020) Development of an ELISA for the quantification of mycolactone, the cytotoxic macrolide toxin of Mycobacterium ulcerans. PLoS Neglected Tropical Diseases, 14 (6). e0008357.

2019

Gehringer, Matthias and Mäder, Patrick and Gersbach, Philipp and Pfeiffer, Bernhard and Scherr, Nicole and Dangy, Jean-Pierre and Pluschke, Gerd and Altmann, Karl-Heinz. (2019) Configurationally stabilized analogs of M. ulcerans exotoxins mycolactones A and B reveal the importance of side chain geometry for mycolactone virulence. Organic Letters, 21 (15). pp. 5853-5857.

2018

Jackson, Scott M. and Manolaridis, Ioannis and Kowal, Julia and Zechner, Melanie and Taylor, Nicholas M. I. and Bause, Manuel and Bauer, Stefanie and Bartholomaeus, Ruben and Bernhardt, Guenther and Koenig, Burkhard and Buschauer, Armin and Stahlberg, Henning and Altmann, Karl-Heinz and Locher, Kaspar P.. (2018) Structural basis of small-molecule inhibition of human multidrug transporter ABCG2. Nature structural & molecular biology, 25 (4). pp. 333-340.

2017

Bieri, Raphael and Scherr, Nicole and Ruf, Marie-Thérèse and Dangy, Jean-Pierre and Gersbach, Philipp and Gehringer, Matthias and Altmann, Karl-Heinz and Pluschke, Gerd. (2017) The macrolide toxin mycolactone promotes bim-dependent apoptosis in Buruli ulcer through inhibition of mTOR. ACS chemical biology, 12 (5). pp. 1297-1307.

2016

Dangy, Jean-Pierre and Scherr, Nicole and Gersbach, Philipp and Hug, Melanie N. and Bieri, Raphael and Bomio, Claudio and Li, Jun and Huber, Sylwia and Altmann, Karl-Heinz and Pluschke, Gerd. (2016) Antibody-Mediated Neutralization of the Exotoxin Mycolactone, the Main Virulence Factor Produced by Mycobacterium ulcerans. PLoS Neglected Tropical Diseases, 10 (6). e0004808.

2013

Scherr, Nicole and Gersbach, Philipp and Dangy, Jean-Pierre and Bomio, Claudio and Li, Jun and Altmann, Karl-Heinz and Pluschke, Gerd. (2013) Structure-activity relationship studies on the macrolide exotoxin mycolactone of Mycobacterium ulcerans. PLoS neglected tropical diseases, Vol. 7, H. 3 , e2143.

2009

Benke, Dietmar and Barberis, Andrea and Kopp, Sascha and Altmann, Karl-Heinz and Schubiger, Monika and Vogt, Kaspar E. and Rudolph, Uwe and Möhler, Hanns. (2009) GABA A receptors as in vivo substrate for the anxiolytic action of valerenic acid, a major constituent of valerian root extracts. Neuropharmacology, 56 (1). pp. 174-181.