Automated protein modelling-the proteome in 3D

Peitsch, M. C. and Schwede, T. and Guex, N.. (2000) Automated protein modelling-the proteome in 3D. Pharmacogenomics, Vol. 1, no. 3. pp. 257-266.

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Official URL: http://edoc.unibas.ch/dok/A5259358

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Functional analysis of the proteins discovered in fully sequenced genomes represent the next major challenge of life science research. Computational methods play an increasingly important role in this activity. Among them, comparative protein modelling will play a major role in this challenge, especially in the light of the Structural Genomics programmes about to be started around the world. In recent years, much progress has been made in automating these methods, enabling the production of models for genome scale problems. In this review we discuss how protein models can be applied to functional analysis, as well as some of the current issues and limitations inherent to these methods.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Computational & Systems Biology > Bioinformatics (Schwede)
UniBasel Contributors:Schwede, Torsten
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
Last Modified:22 Mar 2012 14:26
Deposited On:22 Mar 2012 13:51

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