Raps, Felix C. and Fäseke, Vincent C. and Häussinger, Daniel and Sparr, Christof. (2020) Catalyst‐Controlled Transannular Polyketide Cyclization Cascades: Selective Folding of Macrocyclic Polyketides. Angewandte Chemie, 132 (42). pp. 18548-18552.
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Abstract
The biomimetic synthesis of aromatic polyketides from macrocyclic substrates by means of catalyst-controlled transannular cyclization cascades is described. The macrocyclic substrates, which feature increased stability and fewer conformational states, were thereby transformed into several distinct polyketide scaffolds. The catalyst-controlled transannular cyclizations selectively led to aromatic polyketides with a defined folding and oxygenation pattern, thus emulating β-keto-processing steps of polyketide biosynthesis.
Faculties and Departments: | 05 Faculty of Science > Departement Chemie > Chemie > Organische Chemie (Sparr) |
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UniBasel Contributors: | Sparr, Christof |
Item Type: | Article |
Article Subtype: | Research Article |
Publisher: | Wiley |
ISSN: | 0044-8249 |
Language: | English |
Identification Number: | |
edoc DOI: | |
Last Modified: | 25 Apr 2024 13:36 |
Deposited On: | 25 Apr 2024 13:36 |
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