Kessler, Simon N. and Wegner, Hermann A.. (2012) One-Pot Synthesis of Phthalazines and Pyridazino-aromatics: A Novel Strategy for Substituted Naphthalenes. Organic Letters, 14 (13). pp. 3268-3271.
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Official URL: https://edoc.unibas.ch/94295/
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Abstract
A new one-pot strategy for the synthesis of phthalazines and pyridazino-aromatics starting from aromatic aldehydes has been developed. A variety of substituents ranging from electron withdrawing to donating is tolerated furnishing the desired 1,2-diazine in good to excellent yields. The products have been applied to the bidentate Lewis acid catalyzed inverse electron-demand Diels-Alder (IEDDA) reaction opening a novel two-step entry into substituted naphthalenes, such as Naproxen.
| Faculties and Departments: | 05 Faculty of Science > Departement Chemie > Former Organization Units Chemistry > Organische Synthese (Wegner) |
|---|---|
| UniBasel Contributors: | Wegner, Hermann A. A. |
| Item Type: | Article, refereed |
| Article Subtype: | Research Article |
| Publisher: | American Chemical Society |
| ISSN: | 1523-7060 |
| e-ISSN: | 1523-7052 |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
| Identification Number: |
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| Last Modified: | 19 Apr 2023 06:18 |
| Deposited On: | 19 Apr 2023 06:18 |
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