Klompmaker, J. O. and Janssen, N. and Andersen, Z. J. and Atkinson, R. and Bauwelinck, M. and Chen, J. and de Hoogh, K. and Houthuijs, D. and Katsouyanni, K. and Marra, M. and Oftedal, B. and Rodopoulou, S. and Samoli, E. and Stafoggia, M. and Strak, M. and Swart, W. and Wesseling, J. and Vienneau, D. and Brunekeef, B. and Hoek, G.. (2021) Comparison of associations between mortality and air pollution exposure estimated with a hybrid, a land-use regression and a dispersion model. Environment international, 146. p. 106306.
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Abstract
Introduction; : To characterize air pollution exposure at a fine spatial scale, different exposure assessment methods have been applied. Comparison of associations with health from different exposure methods are scarce. The aim of this study was to evaluate associations of air pollution based on hybrid, land-use regression (LUR) and dispersion models with natural cause and cause-specific mortality.; Methods; : We followed a Dutch national cohort of approximately 10.5 million adults aged 29+ years from 2008 until 2012. We used Cox proportional hazard models with age as underlying time scale and adjusted for several potential individual and area-level socio-economic status confounders to evaluate associations of annual average residential NO2, PM2.5 and BC exposure estimates based on two stochastic models (Dutch LUR, European-wide hybrid) and deterministic Dutch dispersion models.; Results; : Spatial variability of PM2.5 and BC exposure was smaller for LUR compared to hybrid and dispersion models. NO2 exposure variability was similar for the three methods. Pearson correlations between hybrid, LUR and dispersion modeled NO2 and BC ranged from 0.72 to 0.83; correlations for PM2.5 were slightly lower (0.61-0.72). In general, all three models showed stronger associations of air pollutants with respiratory disease and lung cancer mortality than with natural cause and cardiovascular disease mortality. The strength of the associations differed between the three exposure models. Associations of air pollutants estimated by LUR were generally weaker compared to associations of air pollutants estimated by hybrid and dispersion models. For natural cause mortality, we found a hazard ratio (HR) of 1.030 (95% confidence interval (CI): 1.019, 1.041) per 10 μg/m3 for hybrid modeled NO2, a HR of 1.003 (95% CI: 0.993, 1.013) per 10 μg/m3 for LUR modeled NO2 and a HR of 1.015 (95% CI: 1.005, 1.024) per 10 μg/m3 for dispersion modeled NO2.
Faculties and Departments: | 09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) 09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Environmental Exposures and Health Systems Research > Physical Hazards and Health (Röösli) |
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UniBasel Contributors: | de Hoogh, Kees and Vienneau, Danielle |
Item Type: | Article, refereed |
Article Subtype: | Research Article |
ISSN: | 0160-4120 |
Note: | Publication type according to Uni Basel Research Database: Journal article |
Language: | English |
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edoc DOI: | |
Last Modified: | 20 Dec 2022 12:45 |
Deposited On: | 20 Dec 2022 12:45 |
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