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Aldol reactions in water using a beta-cyclodextrin-binding proline derivative

Liu, Kegang and Haussinger, Daniel and Woggon, Wolf-D.. (2007) Aldol reactions in water using a beta-cyclodextrin-binding proline derivative. Synlett, 2007, Vol. 14. pp. 2298-2300.

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Official URL: http://edoc.unibas.ch/dok/A5260125

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Abstract

The aldol reaction of various arom. aldehydes with cyclohexanone catalyzed by the inclusion complex of a proline deriv. and beta-cyclodextrin in water is described.  A series of hydroxyketones was obtained using this method in good yields with anti/syn ratio of up to 99:1 and ee values well above 90%.
Faculties and Departments:05 Faculty of Science
05 Faculty of Science > Departement Chemie > Chemie
UniBasel Contributors:Woggon, Wolf-Dietrich
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Georg Thieme
ISSN:0936-5214
Note:Publication type according to Uni Basel Research Database: Journal article
Last Modified:08 Nov 2012 16:11
Deposited On:22 Mar 2012 13:42

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