Spoerri, Iris and Herms, Stefan and Eytan, O. and Sarig, Ofer and Heinimann, Karl and Sprecher, E. and Itin, Peter H. and Burger, Bettina. (2018) Immune-regulatory genes as possible modifiers of familial pityriasis rubra pilaris - Lessons from a family with PRP and psoriasis. Journal of the European Academy of Dermatology and Venereology : JEADV, 32 (10). e389-e392.
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Official URL: https://edoc.unibas.ch/78586/
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Abstract
The familial form of pityriasis rubra pilaris (PRP) is caused by dominant mutations in the coiled-coiled domain of CARD14; 1; . Different variants in CARD14 have been associated with psoriasis; 2; . As some PRP-causing and psoriasis-associated CARD14 variants showed increased NF-κB activation; 2,3; , inappropriate NF-κB-regulation is thought to be involved in the development of both diseases. This article is protected by copyright. All rights reserved.
| Faculties and Departments: | 03 Faculty of Medicine > Departement Biomedizin > Department of Biomedicine, University Hospital Basel > Dermatology (Itin) |
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| UniBasel Contributors: | Burger, Bettina |
| Item Type: | Article, refereed |
| Article Subtype: | Research Article |
| Publisher: | Wiley |
| ISSN: | 0926-9959 |
| e-ISSN: | 1468-3083 |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
| Identification Number: |
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| Last Modified: | 05 Oct 2020 06:55 |
| Deposited On: | 05 Oct 2020 06:55 |
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