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Nanomechanical mass and viscosity measurement-platform for cell imaging

Oliva, Paolo. Nanomechanical mass and viscosity measurement-platform for cell imaging. 2020, Doctoral Thesis, University of Basel, Faculty of Science.

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Official URL: http://edoc.unibas.ch/diss/DissB_13669

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Abstract

In this thesis, a novel imaging platform using silicon-nitride membranes as nanomechanical resonator is presented. The basic theory lies in the determination of the
mass, the stiffness and the viscosity of randomly distributed mass points lying on the
transducer. The first step of the development was to build a nanomechanical sensing
platform, which was able to characterize a homogeneous fluid. The determined
physical properties are namely the mass density ρ and the dynamic viscosity η.
These properties deliver suitable information about the fluid dynamics: the change
in viscosity could for example be used to investigate protein aggregation or filament
formation.
Advisors:Meyer, Ernst and Stahlberg, Henning and Ghatkesar, Murali-Krishna
Faculties and Departments:05 Faculty of Science > Departement Physik > Physik > Nanomechanik (Meyer)
UniBasel Contributors:Oliva, Paolo and Meyer, Ernst and Stahlberg, Henning
Item Type:Thesis
Thesis Subtype:Doctoral Thesis
Thesis no:13669
Thesis status:Complete
Number of Pages:1 Online-Ressource (iv, 120 Seiten)
Language:English
Identification Number:
Last Modified:03 Sep 2020 04:30
Deposited On:02 Sep 2020 12:13

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