Williams, Margaret and Lidke, Diane S. and Hartmann, Karin and George, Tracy I.. (2019) PD-L1 expression in mastocytosis. International Journal of Molecular Siences, 20 (9). p. 2362.
Full text not available from this repository.
Official URL: https://edoc.unibas.ch/70872/
Downloads: Statistics Overview
Abstract
Programmed death 1 (PD-1), when activated by its ligands PD-L1 and PD-L2, suppresses active immune cells in normal immune regulation to limit autoimmunity and, in tumors, as a mechanism of immune evasion. PD-L1 expression has been described as both a prognostic and predictive marker in many solid and hematologic neoplasms, as targeted therapies against the PD-1/PD-L1 interaction have gained clinical importance. PD-L1 expression has been assessed in a few studies on mastocytosis. We review this literature and the need for further investigation of the tumor-immune interaction in mastocytosis.
Faculties and Departments: | 03 Faculty of Medicine > Departement Biomedizin > Department of Biomedicine, University Hospital Basel > Allergy and Immunity (Hartmann) |
---|---|
UniBasel Contributors: | Hartmann, Karin |
Item Type: | Article, refereed |
Article Subtype: | Research Article |
Publisher: | MDPI |
ISSN: | 1661-6596 |
e-ISSN: | 1422-0067 |
Note: | Publication type according to Uni Basel Research Database: Journal article |
Related URLs: | |
Identification Number: |
|
Last Modified: | 10 Nov 2020 13:11 |
Deposited On: | 10 Nov 2020 13:11 |
Repository Staff Only: item control page