Lugli, Alessandro and Zlobec, Inti and Günthert, Ursula and Minoo, Parham and Baker, Kristi and Tornillo, Luigi and Terracciano, Luigi and Jass, Jeremy R.. (2006) Overexpression of the receptor for hyaluronic acid mediated motility is an independent adverse prognostic factor in colorectal cancer. Modern pathology, Vol. 19, no. 10. pp. 1302-1309.
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Official URL: http://edoc.unibas.ch/dok/A5251314
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Abstract
RHAMM, a member of the microtubule-associated protein family that interacts with the mitogen-activated protein kinase pathway, is associated with tumor progression, aggressive disease and shortened survival in several tumor types. This study aimed to determine the prognostic value of RHAMM in colorectal cancer (CRC). A series of 1420 unselected, nonconsecutive CRC resections were subdivided into three groups: (1) DNA mismatch repair (MMR)-proficient, (2) MLH1 negative and (3) presumed Lynch syndrome. Immunohistochemical analysis of RHAMM expression (0 vs <0%), increasing expression (increasing percentage positivity) and complete expression (100 vs
| Faculties and Departments: | 03 Faculty of Medicine > Bereich Querschnittsfächer (Klinik) > Pathologie USB > Neuro- und Muskelpathologie (Frank) 03 Faculty of Medicine > Departement Klinische Forschung > Bereich Querschnittsfächer (Klinik) > Pathologie USB > Neuro- und Muskelpathologie (Frank) |
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| UniBasel Contributors: | Günthert, Ursula |
| Item Type: | Article, refereed |
| Article Subtype: | Research Article |
| Publisher: | Nature Publishing Group |
| ISSN: | 0893-3952 |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
| Related URLs: | |
| Identification Number: |
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| Last Modified: | 22 Mar 2012 14:23 |
| Deposited On: | 22 Mar 2012 13:35 |
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