Interference of Mycobacterium tuberculosis with macrophage responses

Scherr, N. and Jayachandran, R. and Mueller, P. and Pieters, J.. (2009) Interference of Mycobacterium tuberculosis with macrophage responses. Indian Journal of Experimental Biology, Vol. 47, H. 6. pp. 401-406.

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Official URL: http://edoc.unibas.ch/dok/A5259385

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Tuberculosis, caused by Mycobacterium tuberculosis, has become an important health and economic burden, with more than four thousand people succumbing to the disease every day. Thus, there is an urgent need to understand the molecular basis of this pathogen's success in causing disease in humans, in order to develop new drugs superior to conventional drugs available at present. One reason why M. tuberculosis is such a dangerous microbe lies within its ability to survive within infected hosts, thereby efficiently circumventing host immune responses. Over the past few years, a number of mechanisms have been unravelled that are utilized by M. tuberculosis to survive within hosts and to avoid immune defence mechanisms. Several of these mechanisms have been described in this communication that may be useful for the development of novel compounds to treat tuberculosis.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Infection Biology > Biochemistry (Pieters)
UniBasel Contributors:Pieters, Jean
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:31 Dec 2015 10:44
Deposited On:22 Mar 2012 13:32

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