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Scaling laws in functional genome content across prokaryotic clades and lifestyles

Molina, N. and van Nimwegen, E.. (2009) Scaling laws in functional genome content across prokaryotic clades and lifestyles. Trends in genetics, Vol. 25, H. 6. pp. 243-247.

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Official URL: http://edoc.unibas.ch/dok/A5259618

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Abstract

For high-level functional categories that are represented in almost all prokaryotic genomes, the numbers of genes in these categories scale as power-laws in the total number of genes. We present a comprehensive analysis of the variation in these scaling laws across prokaryotic clades and lifestyles. For the large majority of functional categories, including transcription regulators, the inferred scaling laws are statistically indistinguishable across clades and lifestyles, supporting the simple hypothesis that these scaling laws are universally shared by all prokaryotes.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Computational & Systems Biology > Bioinformatics (van Nimwegen)
UniBasel Contributors:van Nimwegen, Erik
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Elsevier
ISSN:0168-9525
Note:Publication type according to Uni Basel Research Database: Journal article
Last Modified:22 Mar 2012 14:22
Deposited On:22 Mar 2012 13:31

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