edoc

Challenges for brain repair: insights from adult neurogenesis in birds and mammals

Doetsch, F. and Scharff, C.. (2001) Challenges for brain repair: insights from adult neurogenesis in birds and mammals. Brain, Behavior and Evolution, 58 (5). pp. 306-322.

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Abstract

Adult neurogenesis is a widespread phenomenon occurring in many species, including humans. The functional and therapeutic implications of this form of brain plasticity are now beginning to be realized. Comparative approaches to adult neurogenesis will yield important clues about brain repair. Here, we compare adult neurogenesis in birds and mammals. We review recent studies on the glial identity of stem cells that generate new neurons, the different modes of migration used by the newly generated neurons to reach their destinations, and how these systems respond to experimentally induced cell death. We integrate these findings to address how comparative analysis at the molecular level might be used for brain repair.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Neurobiology > Stem Cell Biology (Doetsch)
UniBasel Contributors:Doetsch, Fiona
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Karger
ISSN:0006-8977
e-ISSN:1421-9743
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
Identification Number:
Last Modified:30 May 2018 09:52
Deposited On:23 Nov 2017 11:12

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