Encoding stimulus information by spike numbers and mean response time in primary auditory cortex

Nelken, Israel and Chechik, Gal and Mrsic-Flogel, Thomas D. and King, Andrew J. and Schnupp, Jan W. H.. (2005) Encoding stimulus information by spike numbers and mean response time in primary auditory cortex. Journal of Computational Neuroscience, 19 (2). pp. 199-221.

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Official URL: http://edoc.unibas.ch/49655/

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Neurons can transmit information about sensory stimuli via their firing rate, spike latency, or by the occurrence of complex spike patterns. Identifying which aspects of the neural responses actually encode sensory information remains a fundamental question in neuroscience. Here we compared various approaches for estimating the information transmitted by neurons in auditory cortex in two very different experimental paradigms, one measuring spatial tuning and the other responses to complex natural stimuli. We demonstrate that, in both cases, spike counts and mean response times jointly carry essentially all the available information about the stimuli. Thus, in auditory cortex, whereas spike counts carry only partial information about stimulus identity or location, the additional availability of relatively coarse temporal information is sufficient in order to extract essentially all the sensory information available in the spike discharge pattern, at least for the relatively short stimuli (
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Former Organization Units Biozentrum > Neural Networks (Mrsic-Flogel)
UniBasel Contributors:Mrsic-Flogel, Thomas
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:27 Nov 2017 07:57
Deposited On:27 Nov 2017 07:57

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