Lifelong learning: ocular dominance plasticity in mouse visual cortex

Hofer, Sonja B. and Mrsic-Flogel, Thomas D. and Bonhoeffer, Tobias and Hübener, Mark. (2006) Lifelong learning: ocular dominance plasticity in mouse visual cortex. Current Opinion in Neurobiology, 16 (4). pp. 451-459.

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Official URL: http://edoc.unibas.ch/49614/

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Ocular dominance plasticity has long served as a successful model for examining how cortical circuits are shaped by experience. In this paradigm, altered retinal activity caused by unilateral eye-lid closure leads to dramatic shifts in the binocular response properties of neurons in the visual cortex. Much of the recent progress in identifying the cellular and molecular mechanisms underlying ocular dominance plasticity has been achieved by using the mouse as a model system. In this species, monocular deprivation initiated in adulthood also causes robust ocular dominance shifts. Research on ocular dominance plasticity in the mouse is starting to provide insight into which factors mediate and influence cortical plasticity in juvenile and adult animals.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Former Organization Units Biozentrum > Neuronal circuits and brain function (Hofer)
UniBasel Contributors:Hofer, Sonja and Mrsic-Flogel, Thomas
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:27 Nov 2017 12:56
Deposited On:27 Nov 2017 12:56

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