Novel proteasome inhibitors as potential drugs to combat tuberculosis

Cheng, Yong and Pieters, Jean. (2010) Novel proteasome inhibitors as potential drugs to combat tuberculosis. Journal of Molecular Cell Biology, 2 (4). pp. 173-175.

PDF - Published Version

Official URL: http://edoc.unibas.ch/45699/

Downloads: Statistics Overview


Mycobacterium tuberculosis is one of the most notorious killers worldwide. These pathogens have evolved to infect human beings in a so-called dormant form that is extremely difficult to treat. New work, however, suggests that mycobacterial proteasomes, multicomponent structures that protect the microbe from damaging effects of nitric oxide generated by the host, can be selectively and specifically blocked by small molecules.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Infection Biology > Biochemistry (Pieters)
UniBasel Contributors:Pieters, Jean
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Oxford University Press
Note:Publication type according to Uni Basel Research Database: Journal article
Identification Number:
edoc DOI:
Last Modified:08 Nov 2017 11:34
Deposited On:03 Jan 2017 15:51

Repository Staff Only: item control page